136058-65-6

Basic information

• Product Name: 5-[1-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-phenyl}-meth-(Z)-ylidene]-2-thioxo-oxazolidin-4-one
• Synonyms: 5-[1-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-phenyl}-meth-(Z)-ylidene]-2-thioxo-oxazolidin-4-one
• CAS NO: 136058-65-6
• Molecular Weight: 418.473
• Mol File: 136058-65-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[1-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-phenyl}-meth-(Z)-ylidene]-2-thioxo-oxazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[1-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-phenyl}-meth-(Z)-ylidene]-2-thioxo-oxazolidin-4-one(136058-65-6)
• EPA Substance Registry System: 5-[1-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-phenyl}-meth-(Z)-ylidene]-2-thioxo-oxazolidin-4-one(136058-65-6)

Safety Data

• Hazardous Substances Data: 136058-65-6(Hazardous Substances Data)

Upstream product

• 2346-24-9 2-thio-2,4-oxazolidinedione 
• 125531-53-5 4-[3-(5-Methyl-2-phenyl-4-oxazolyl)propionyl]benzaldehyde 

Downstream Products

• 132672-21-0 5-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-benzyl}-oxazolidine-2,4-dione 
• 136058-66-7 5-[1-{4-[3-(5-Methyl-2-phenyl-oxazol-4-yl)-propionyl]-phenyl}-meth-(Z)-ylidene]-oxazolidine-2,4-dione 

Relevant articles and documents

Benzyloxazolidine-2,4-diones as potent hypoglycemic agents

A series of benzyloxazolidine-2,4-diones, containing oxazole-based side chains, were found to lower blood glucose levels in the genetically obese ob/ob mouse. Incorporation of a benzofuran structural element in these compounds provides greatly enhanced in vivo potency. The syntheses and structure-activity relationships for this series are detailed.