50385-24-5

Usage

Synthetic organic compound

It is a man-made compound that is synthesized through chemical reactions.

Pyridine derivative

It belongs to a family of compounds that are derived from pyridine, which is a heterocyclic aromatic compound with a nitrogen atom in the ring.

Pyridine ring

It is a six-membered aromatic ring system that is present in the compound, which is the basis of its chemical structure.

2-(2-nitrophenyl)ethenyl group

This is a functional group that is attached to the pyridine ring, which consists of a phenyl group (a six-membered aromatic ring with a hydrogen atom replaced by a nitro group) and an ethenyl group (a two-carbon chain with a double bond between the carbons).

Used in organic synthesis and pharmaceutical research

The compound is commonly used in the synthesis of other compounds and in the development of new drugs due to its potential pharmacological properties.

Potential pharmacological properties

The compound has not yet been fully studied, but it has the potential to have effects on biological systems that could be useful in the development of new drugs.

Specific uses and potential effects still being studied

While the compound has potential uses in the pharmaceutical industry, its specific effects and applications are still being researched and have not yet been fully determined.

Upstream product

• 109-06-8 α-picoline 
• 552-89-6 2-nitro-benzaldehyde 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 1121-60-4 pyridine-2-carbaldehyde 
• 23308-83-0 (2-nitrobenzyl)triphenylphosphonium bromide 

Downstream Products

• 105376-41-8 2-(2-pyridin-2-yl-vinyl)-aniline 
• 13228-40-5 2-(2-pyridinyl)-1H-indole 
• 71978-20-6 3-(pyridin-2-yl)quinolin-2(1H)-one 
• 58754-46-4 (S)-2'-[2-(1-methyl-2-piperidyl)ethyl]cinnamanilide 
• 1360685-63-7 (S)-[2-(o-aminophenethyl)-1-methylpiperidine dibenzoyl-L-tartrate] 
• 210282-36-3 2-(o-aminophenethyl)-1-methylpiperidine hydroiodide 

Relevant academic research and scientific papers

Access to [2,1]benzothiazine s,s-dioxides from β-substituted o-nitrostyrenes and sulfur

[2,1]Benzothiazine S,S-dioxides 2 were synthesized by simply heating o-nitrostyrenes with elemental sulfur in 3- picoline with complete atom economy. This reaction was found to occur without any added catalyst and consist of a cascade of reduction of the

Structural development of tetrachlorophthalimides as liver X receptor β (LXRβ)-selective agonists with improved aqueous solubility

LXRβ-selective agonists are promising candidates to improve atherosclerosis without increasing plasma or hepatic TG levels. We have reported a series of tetrachlorophthalimide analogs as an LXRβ-selective agonist. However, they exhibited poor aqueous solubility probably due to its high hydrophobicity and highly rigid and plane structure. In this report, we present further structural development of tetrachloro(styrylphenyl)phthalimides as the LXRβ-selective agonists with improved aqueous solubility.

METHODS AND COMPOSITIONS FOR TREATING HEMORRHOIDS WHILE PROVIDING LOCAL ANESTHETIC AND ANTI-INFLAMMATORY EFFECTS

The present invention relates to compositions and methods for treatment of internal and/or external hemorrhoids, wherein the treatment includes topically administering to a subject a composition comprising from 0.3% to 0.7% of S-2'- [2-(1-methyl-2- piperidyl) ethyl] cinnamanilide, wherein the S-2'- [2-(1-methyl-2-piperidyl) ethyl] cinnamanilide not only treats the hemorrhoidal symptoms but exhibits a local anesthetic effect while controlling inflammation in the area of treatment.

METHODS AND COMPOSITIONS FOR TREATING INTERNAL AND EXTERNAL HEMORRHOIDS

The present invention relates to compositions and methods for treatment of internal and/or external hemorrhoids, wherein the treatment includes topically administering to a subject a composition comprising from 0.3% to 0.7% of S-2'- [2-(l-methyl-2- piperi

Pyridine derivatives

A compound of formula I wherein X represents an optionally halo-substituted (C2-4)alkynylene group bonded via vicinal unsaturated carbon atoms.