1361026-00-7Relevant academic research and scientific papers
Syntheses, neural protective activities, and inhibition of glycogen synthase kinase-3β of substituted quinolines
Lu, Jianyu,Maezawa, Izumi,Weerasekara, Sahani,Erenler, Ramazan,Nguyen, Tuyen D.T.,Nguyen, James,Swisher, Luxi Z.,Li, Jun,Jin, Lee-Way,Ranjan, Alok,Srivastava, Sanjay K.,Hua, Duy H.
, p. 3392 - 3397 (2014/07/22)
A new series of fifteen 5-, 6-, and 8-appended 4-methylquinolines were synthesized and evaluated for their neural protective activities. Selected compounds were further examined for their inhibition of glycogen synthase kinase-3β (GSK-3β) and protein kina
Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs
Chaurasiya, Narayan D.,Ganesan, Shobana,Nanayakkara, N.P. Dhammika,Dias, Luiza R.S.,Walker, Larry A.,Tekwani, Babu L.
scheme or table, p. 1701 - 1704 (2012/04/04)
8-Aminoquinolines (8-AQs) are important class of anti-infective therapeutics. 5-Phenoxy 8-aminoquinoline analogs have shown improved metabolic stability compared to primaquine. In view or predictive role of monoamine oxidases (MAO) in metabolism of 8-amin
