1361146-90-8Relevant articles and documents
Synthesis of Two Key Fragments of the Complex Polyhalogenated Marine Meroterpenoid Azamerone
Schnell, Simon D.,Linden, Anthony,Gademann, Karl
, p. 1144 - 1147 (2019/05/16)
A concise route toward two advanced fragments in the context of the total synthesis of the unique natural product azamerone is reported. Key synthetic features include the enantioselective synthesis of an epoxysilane and its Lewis-acid-induced cyclization and the installation of the pyridazine ring via a formylation/condensation sequence. This route provides strategic insights into the chemistry of phthalazinediols, facilitating synthetic approaches toward this class of natural products.
Enantiomerically enriched tris(boronates): Readily accessible conjunctive reagents for asymmetric synthesis
Coombs, John R.,Zhang, Liang,Morken, James P.
supporting information, p. 16140 - 16143 (2015/01/09)
The catalytic enantioselective diboration of vinyl boronate esters furnishes chiral tris(boronates) in a selective fashion. Subsequent deborylative alkylation occurs in a diastereoselective fashion, both for intermolecular and intramolecular processes.