1361200-95-4Relevant academic research and scientific papers
Selective preparation of functionalized dienes from allylic phosphonium salts through the wittig reaction
Sa, Marcus M.,Meier, Lidiane
, p. 384 - 391 (2013)
A convenient and general method for the synthesis of stereochemically defined dienes from allylic phosphonium salts under simple conditions is described. Selective preparation of trisubstituted dienes was performed with good-to-excellent yields in mild ba
Synthesis of 3-( ?3,δ-disubstituted)allylidene-2-oxindoles from isatins by Wittig reaction with Morita-Baylis -Hillman bromides
Moon, Hye Ran,Kim, Ko Hoon,Lee, Junseong,Kim, Jae Nyoung
, p. 219 - 225 (2015/03/05)
Various 3-(?3,??-disubstituted)allylidene-2-oxindoles were synthesized by the Wittig reaction between isatins and the phosphorous ylide derived in situ from the Morita-Baylis -Hillman bromides. The 3-allylidene-2-oxindole could be used as an efficient syn
Microwave-assisted synthesis of the (E)-α-methylalkenoate framework from multifunctionalized allylic phosphonium salts
Meier, Lidiane,Ferreira, Misael,Sa, Marcus M.
experimental part, p. 179 - 186 (2012/07/14)
A convenient and general microwave-assisted method for the synthesis of stereochemically defined α-methylalkenoic acids and esters from allylic phosphonium salts in a basic aqueous medium is described. A selective preparation of acids or esters was dependent on the base (NaOH or NaHCO 3) employed in the reaction and could be achieved with good to excellent yields under mild conditions in the absence of hydrides and reducing agents.
Synthesis of enantiomerically pure 3-amino-2-methylenealkanoates (Aza-Morita-Baylis-Hillman adducts) mediated by cinchona alkaloids
Martelli, Gianluca,Orena, Mario,Rinaldi, Samuele
supporting information; experimental part, p. 7199 - 7206 (2012/01/16)
3-Substituted (Z)-2-(bromomethyl)propenoates reacted with (S)-1-(4-methoxyphenyl)ethylamine in the presence of astoichiometric amount of quinidine to yield (R)-3-[(tert-butoxycarbonyl)amino]-2-methylenealkanoates (aza-Morita-Baylis-Hillman adducts) in ena
