1361409-69-9

Basic information

• Product Name: N-(2-(2-chloro-5-(dimethylamino)phenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)-4-fluorobenzamide
• Synonyms: N-(2-(2-chloro-5-(dimethylamino)phenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)-4-fluorobenzamide
• CAS NO: 1361409-69-9
• Molecular Weight: 488.009
• Mol File: 1361409-69-9.mol

Chemical Properties

• CAS DataBase Reference: N-(2-(2-chloro-5-(dimethylamino)phenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)-4-fluorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(2-chloro-5-(dimethylamino)phenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)-4-fluorobenzamide(1361409-69-9)
• EPA Substance Registry System: N-(2-(2-chloro-5-(dimethylamino)phenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)-4-fluorobenzamide(1361409-69-9)

Safety Data

• Hazardous Substances Data: 1361409-69-9(Hazardous Substances Data)

Upstream product

• 1694-29-7 3-chloropentane-2,4-dione 
• 456-22-4 4-Fluorobenzoic acid 
• 1350650-02-0 N⁽²⁾-(2-chloro-5-(dimethylamino)phenyl)-4'-methyl-[4,5'-bithiazole]-2,2'-diamine 
• 403-43-0 4-fluorobenzoyl chloride 
• 30748-47-1 5-acetyl-4-methylthiazole-2-amine 
• 32519-72-5 1-(2-amino-4-methylthiazol-5-yl)-2-bromoethanone 

Relevant articles and documents

Fluorinated DF508-CFTR correctors and potentiators for PET imaging

19F-modified bithiazole correctors and phenylglycine potentiators of the DF508-CFTR chloride channel were synthesized and their function assayed in cells expressing human DF508-CFTR and a halide-sensitive fluorescent protein. Fluorine was incorporated into each scaffold using prosthetic groups for future biodistribution imaging studies using positron emission tomography (PET). The DF508-CFTR corrector and potentiator potencies of the fluorinated analogs were comparable to or better than those of the original compounds.