1361748-71-1

Upstream product

• 1361567-63-6 C₁₃H₈Cl₃NO₂ 
• 365413-29-2 6-chloro-5-iodonicotinic acid methyl ester 
• 365413-19-0 6-hydroxy-5-iodonicotinic acid 
• 885950-46-9 6-hydroxy-5-iodonicotinic acid methyl ester 
• 66171-50-4 methyl 6-hydroxynicotinate 
• 151169-75-4 3,4-dichlophenylboronic acid 
• 5006-66-6 6-hydroxy-3-pyridinecarboxylic acid 

Downstream Products

• 1373754-96-1 5-(3,4-dichloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid 
• 1269826-44-9 5-(3,4-dichlorophenyl)-N-((1R,2R)-2-hydroxycyclohexyl)-6-(2,2,2-trifluoroethoxy)nicotinamide 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF NICOTINAMIDE DERIVATIVES

The present invention relates to a process for the preparation of nicotinamide derivatives of formula I, wherein R1 to R7 are as defined above and to pharmaceutically acceptable salts thereof. The compounds of formula I are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of cannabinoid 1 receptors (CB1 receptors) as described in the PCT Publ. WO 2006/106054.

PROCESS FOR THE PREPARATION OF NICOTINAMIDE DERIVATIVES

The present invention relates to a process for the preparation of nicotinamide derivatives of the formula (I) R1 to R7 are as defined in the and to pharmaceutically acceptable salts thereof. The compounds of formula (I) are useful for the treatment and / or prophylaxis of diseases which are associated with the modulation of cannabinoid 1 receptors (CB 1 receptors) as described in the PCT Publ. WO 2006/106054.