136186-07-7 Usage
Uses
Used in Pharmaceutical Applications:
(Z)-2-Cyano-3-(3,5-dichloro-phenyl)-3-hydroxy-N-(4-trifluoromethyl-phenyl)-acrylamide is used as a compound with potential pharmaceutical applications due to its possible antitumor and antiviral properties. It is being studied for its effectiveness in treating various types of cancer and viral infections, making it a promising candidate for drug development.
Used in Research Applications:
In the field of research, (Z)-2-Cyano-3-(3,5-dichloro-phenyl)-3-hydroxy-N-(4-trifluoromethyl-phenyl)-acrylamide serves as an important compound for investigating its biological activities and potential interactions with biological systems. Its unique structure allows researchers to explore its properties and possible applications in the development of new therapeutic agents.
Used in Chemical Synthesis:
(Z)-2-Cyano-3-(3,5-dichloro-phenyl)-3-hydroxy-N-(4-trifluoromethyl-phenyl)-acrylamide may also be used as a building block or intermediate in the synthesis of more complex molecules with specific applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 136186-07-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,1,8 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 136186-07:
(8*1)+(7*3)+(6*6)+(5*1)+(4*8)+(3*6)+(2*0)+(1*7)=127
127 % 10 = 7
So 136186-07-7 is a valid CAS Registry Number.
136186-07-7Relevant academic research and scientific papers
Synthesis and Biological Activity of a Series of Diaryl-Substituted α-Cyano-β-hydroxypropenamides, a New Class of Anthelmintic Agents
Sjogren, Eric B.,Rider, Michael A.,Nelson, Peter H.,Bingham, Stanford,Poulton, Anthony L.,et al.
, p. 3295 - 3301 (2007/10/02)
A series of α-cyano-β-hydroxypropenamides was prepared and tested for anthelmintic activity. α-Cyano-β-hydroxy-N--3-propenamide (1) showed good activity against the nematode Nematospirodes dubius in a mixed parasite infection in mice; several of the analogues were also effective against the cestode Hymenolepis nana.In sheep trials, 1 caused 100percent reduction of the hematophagous nematode Haemonchus contortus after a single dose of 20 mg/kg but did not show satisfactory control of Trichostrongylus colubriformis or Ostertagia circumcincta.Against the liver fluke Fasciola hepatica, 1 suppressed egg production but only temporarily, suggesting that the adult flukes were not eliminated.Mechanism of action studies on 1 using Ascaris mitochondria showed it to be an uncoupler of oxidative phosphorylation.
