1361927-95-8

Upstream product

• 1004-66-6 2-methoxy-1,3-dimethylbenzene 
• 78-84-2 isobutyraldehyde 
• 75-05-8 acetonitrile 

Downstream Products

• 1515875-79-2 2-hydroxy-3-{(3,3,7,9-tetramethyl-8-oxo-2-azaspiro[4.5]deca-1,6,9-trien-1-yl)methyl}-3-(4-chlorobenzoyl)pyrrolo[1,2-a]quinoxaline-1,4(3aH,5H)-dione 
• 1515875-78-1 2-hydroxy-3-(4-methoxybenzoyl)-3-{(3,3,7,9-tetramethyl-8-oxo-2-azaspiro[4.5]deca-1,6,9-trien-1-yl)methyl}pyrrolo[1,2-a]quinoxaline-1,4(3aH,5H)-dione 
• 1515875-77-0 2-hydroxy-3-{(3,3,7,9-tetramethyl-8-oxo-2-azaspiro[4.5]deca-1,6,9-trien-1-yl)methyl}-3-(4-toluoyl)pyrrolo[1,2-a]quinoxaline-1,4(3aH,5H)-dione 
• 1515875-76-9 3-benzoyl-2-hydroxy-3-{(3,3,7,9-tetramethyl-8-oxo-2-azaspiro[4.5]deca-1,6,9-trien-1-yl)methyl}pyrrolo[1,2-a]quinoxaline-1,4(3aH,5H)-dione 

Relevant academic research and scientific papers

Ritter reaction. Synthesis of 1-substituted 3,3,7,9-tetramethyl-2- azaspiro[4.5]deca-6,9-dien- and -1,6,9-trien-8-ones and 7-methoxy-3,3,6,8- tetramethyl-3,4-dihydroisoquinolines

1-(4-Methoxy-3,5-dimethylphenyl)-2-methylpropan-1-ol reacted with nitriles [MeSCN, PhCN, MeCN, EtOC(O)CH2CN] in the presence of concentrated sulfuric acid to give both 1-R-3,3,7,9-tetramethyl-2-azaspiro[4,5]deca-6,9-dien- and -1,6,9-trien-8-one