136272-24-7Relevant academic research and scientific papers
Organophotoredox-Catalyzed Three-Component Coupling of Heteroatom Nucleophiles, Alkenes, and Aliphatic Redox Active Esters
Shibutani, Shotaro,Nagao, Kazunori,Ohmiya, Hirohisa
, p. 1798 - 1803 (2021)
This manuscript describes a visible-light-mediated organophotoredox catalytic process for vicinal difunctionalization of alkenes using heteroatom nucleophiles and aliphatic redox active esters. A wide range of heteroatom nucleophiles including alcohols, water, carboxylic acids, amides, and halogens can be used for this reaction. This radical relay type reaction allows forging of C(sp3)-C(sp3) with a carbon-centered radical and C(sp3)-heteroatom bonds with a benzyl cation on the vinylarenes with complete regioselectivity in a single step.
