136347-10-9Relevant academic research and scientific papers
Highly Diastereoselective Hydrocyanation of β-Keto Sulfoxides: Synthesis of Enantiomerically Pure Cyanohydrin Derivatives
Ruano, Jose L. Garcia,Castro, Ana M. Martin,Rodriguez, Jesus H.
, p. 7235 - 7241 (2007/10/02)
The reactions of chiral β-keto sulfoxides, R1-CO-CHR2-SOTol (R1 = Me, n-Pr, i-Pr, t-Bu, Ph; R2 = H, Me) with Et2AlCN yield the corresponding sulfinyl cyanohydrins with high yields (85-96percent) and de (>96perce
Reactions of chiral β-ketosulfoxides with Et2AlCN: Asymmetric synthesis of cyanohydrin derivatives
Garcia Ruano,Martin Castro,Rodriguez
, p. 3195 - 3198 (2007/10/02)
The reaction of chiral p-tolylsulfinylmethyl ketones (R-CO-CH2-SOTol, R=Ph, Et and t-Bu) with Et2AlCN, yields almost optically pure sulfinyl cyanohydrins (d.e. ≥ 96%). The reaction was quicker in the presence of ZnCl2, but
