136386-58-8Relevant academic research and scientific papers
Construction of trifluoromethylated quaternary stereocenters: Via p -quinone methides
Terashima, Kyu,Kawasaki-Takasuka, Tomoko,Agou, Tomohiro,Kubota, Toshio,Yamazaki, Takashi
supporting information, p. 3031 - 3034 (2020/03/19)
Development of a new synthetic method for the construction of quaternary centers with a trifluoromethyl group was realized by way of 1,6-addition of various nucleophiles including active methylene compounds to highly reactive δ-trifluoromethylated p-quinone methides generated in situ from the corresponding tertiary carbonates with a catalytic amount of an appropriate base.
The Synthesis Of Substituted Aryl Diazirines. A Bifunctional Reagent Suitable For Application To Photoaffinity Labelling Studies.
Baldwin, Jack E.,Jesudason, Cynthia D.,Moloney, Mark G.,Morgan, D. Rhys,Pratt, Andrew J.
, p. 5603 - 5614 (2007/10/02)
The 1,3,5-trisubstituted aryl diazirine (2) has been synthesised as a photoaffinity probe and has been elaborated to a reagent suitable for application to studies of penicillin and cephalosporin biosynthetic enzymes.Keywords: photoaffinity; diazirine; bif
