1364322-41-7 Usage
Uses
Used in Pharmaceutical Industry:
Entacapone EP Impurity G is used as an impurity in the manufacturing process of Entacapone for its role in the treatment of Parkinson's disease. As a peripherally acting inhibitor of COMT, it helps in the metabolism of catecholamine neurotransmitters and related drugs, providing antiparkinsonian effects.
Entacapone EP Impurity G is also used as a reference material for quality control and analytical purposes in the pharmaceutical industry. It ensures the purity and potency of Entacapone, which is crucial for its effectiveness in treating Parkinson's disease.
Check Digit Verification of cas no
The CAS Registry Mumber 1364322-41-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,4,3,2 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1364322-41:
(9*1)+(8*3)+(7*6)+(6*4)+(5*3)+(4*2)+(3*2)+(2*4)+(1*1)=137
137 % 10 = 7
So 1364322-41-7 is a valid CAS Registry Number.
1364322-41-7Relevant academic research and scientific papers
Efficient approach to pure entacapone and related compounds
Srikanth,Ray, Uttam Kumar,Srinivas Rao,Gupta, P. Badarinadh,Lavanya,Islam, Aminul
, p. 1359 - 1366 (2012/04/04)
A new and efficient process through a new intermediate, (2E)-2-cyano-3-(3,4-dihydroxy-5-nirtrophenyl)prop-2-enoic acid 15, has been described for preparing substantially pure entacapone 1. This new intermediate 15 was prepared by Knoevenagel condensation of 3,4-dihydroxy-5-nitrobenzaldehyde 2 with 2-cyanoacetic acid 14 and was further condensed with diethylamine to get pure entacapone 1. Some of the important process-related impurities of entacapone (17, 18, 19, and 20) were also prepared easily from this intermediate 15. Copyright Taylor & Francis Group, LLC.
