1364569-38-9

Basic information

• Product Name: tert-butyl 3-benzyl-3-(difluoromethyl)-2-oxopyrrolidine-1-carboxylate
• CAS NO: 1364569-38-9
• Molecular Weight: 325.355
• Mol File: 1364569-38-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-benzyl-3-(difluoromethyl)-2-oxopyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-benzyl-3-(difluoromethyl)-2-oxopyrrolidine-1-carboxylate(1364569-38-9)
• EPA Substance Registry System: tert-butyl 3-benzyl-3-(difluoromethyl)-2-oxopyrrolidine-1-carboxylate(1364569-38-9)

Safety Data

• Hazardous Substances Data: 1364569-38-9(Hazardous Substances Data)

Upstream product

• 75-46-7 trifluoromethan 
• 1015069-81-4 tert-butyl 3-benzyl-2-oxopyrrolidine-1-carboxylate 

Relevant articles and documents

Umpolung of fluoroform by C-F bond activation: Direct difluoromethylation of lithium enolates

Double agent: The direct α-difluoromethylation of lithium enolates using an umpolung form of fluoroform as a difluoromethyl carbocation equivalent leads to an all-carbon quaternary center. Late transition metals are not necessary and the reaction involves activation of inert C-F bonds with subsequent C-C bond formation. Copyright