1015069-81-4Relevant articles and documents
Synthesis of quaternary α-perfluoroalkyl lactams via electrophilic perfluoroalkylation
Katayev,Václavík,Brüning,Commare,Togni
, p. 4049 - 4052 (2016)
Efficient protocols enabling the rapid installation of trifluoromethyl, as well as further functionalized fluoroalkyl groups by an electrophilic perfluoroalkylation of lactam-derived ketene silyl amides (KSAs) using hypervalent iodine reagents 1 and 2 have been developed.
Amino-substituted heterocycles, compositions thereof, and methods of treatment therewith
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Page/Page column 55, (2008/12/07)
Provided herein are Heterocyclic Compounds having the following structure: wherein R1, R2, X, Y and Z are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heterocyclic Compound to a patient in need thereof.