136458-75-8

Upstream product

• 87326-90-7 methyl 4-O-acetyl-2,3-di-O-benzyl-6-deoxy-α-D-xylo-hex-5-enopyranoside 
• 136386-48-6 methyl 4-O-acetyl-2,3-di-O-benzyl-6-deoxy-β-L-arabino-hex-5-enopyranoside 
• 29388-46-3 methyl 2,3-di-O-benzyl-α-D-galactopyranoside 
• 130703-27-4 methyl 2,3-di-O-benzyl-6-O-tosyl-α-D-galactopyranoside 
• 136386-53-3 methyl 4-O-acetyl-2,3-di-O-benzyl-6-deoxy-6-iodo-α-D-galactopyranoside 

Downstream Products

• 136458-74-7 2L-(2,4/3)-2-O-acetyl-3,4-di-O-benzyl-2,3,4-trihydroxy-5-cyclohexen-1-one 

Relevant academic research and scientific papers

Synthesis of Optically Active Substituted Cyclohexenones from Carbohydrates by Catalytic Ferrier Rearrangement

Conversion of hex-5-enopyranosides into substituted cyclohexenones (Ferrier rearrangement) was found to proceed efficiently with a catalytic amount of various mercury(II) salts at room temperature in a neutral solvent system.Among the mercury(II) salts tested, mercury(II) trifluoroacetate showed the highest activity.Four optically active cyclohexenones were prepared from hex-5-enopyranosides utilizing this method.

Total Synthesis of Antibiotic Hygromycin A

The first total synthesis of the antibiotic (-)-hygromycin A (1) has been achieved by a coupling reaction of the sugar moiety (2) and the cyclitol moiety (3).Both components were synthesized in homochiral forms starting from D-glucose.This synthesis fully