136459-46-6

Basic information

• Product Name: (2R)-3-azido-2-hydroxypropyl p-toluenesulfonate
• Synonyms: (2R)-3-azido-2-hydroxypropyl p-toluenesulfonate
• CAS NO: 136459-46-6
• Molecular Weight: 271.297
• Mol File: 136459-46-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R)-3-azido-2-hydroxypropyl p-toluenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-3-azido-2-hydroxypropyl p-toluenesulfonate(136459-46-6)
• EPA Substance Registry System: (2R)-3-azido-2-hydroxypropyl p-toluenesulfonate(136459-46-6)

Safety Data

• Hazardous Substances Data: 136459-46-6(Hazardous Substances Data)

Upstream product

• 136404-79-0 (R)-1-azido-2-trimethylsilyloxy-3-tosyloxypropane 
• 113826-06-5 (R)-glycidyl tosylate 
• 445030-22-8 (S)-4-tosyloxymethyl-1,3,2-dioxathiolane-2,2-dioxide 
• 41274-09-3 (R)-3-tosyloxy-1,2-propanediol 
• 98-59-9 p-toluenesulfonyl chloride 
• 70987-78-9 (S)-Glycidyl tosylate 
• 23788-74-1 (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate 

Downstream Products

• 285562-01-8 (S)-α-(azidomethyl)-4-[2-(1-methylethoxy)phenyl]-1-piperazineethanol 

Relevant articles and documents

Nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate with various nucleophiles: A comparative study

The nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate tosylate have been carried out with a number of nucleophiles to study the possible attack of nucleophiles at C1, C2 or C3 positions. The regioselectivity and reactivity of both the substrates i.e. epoxide tosylate 1 and the corresponding cyclic sulfate 2 have been compared and established that under similar conditions cyclic sulfate counterpart shows better regioselectivity and better reactivity than the corresponding epoxide.