445030-22-8

Basic information

• Product Name: (S)-4-tosyloxymethyl-1,3,2-dioxathiolane-2,2-dioxide
• Synonyms: (S)-4-tosyloxymethyl-1,3,2-dioxathiolane-2,2-dioxide
• CAS NO: 445030-22-8
• Molecular Weight: 308.333
• Mol File: 445030-22-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-tosyloxymethyl-1,3,2-dioxathiolane-2,2-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-tosyloxymethyl-1,3,2-dioxathiolane-2,2-dioxide(445030-22-8)
• EPA Substance Registry System: (S)-4-tosyloxymethyl-1,3,2-dioxathiolane-2,2-dioxide(445030-22-8)

Safety Data

• Hazardous Substances Data: 445030-22-8(Hazardous Substances Data)

Upstream product

• 23788-74-1 (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate 
• 41274-09-3 (R)-3-tosyloxy-1,2-propanediol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 136459-46-6 (2R)-3-azido-2-hydroxypropyl p-toluenesulfonate 
• 146459-54-3 (S)-3-fluoro-2-hydroxypropyl-4-methylbenzene sulfonate 
• 56715-24-3 (R)-1-(tosyloxy)-3-(1-naphthyloxy)-2-propanol 
• 445030-32-0 (R)-1-benzylamino-3-tosyloxypropan-2-ol 

Relevant articles and documents

Nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate with various nucleophiles: A comparative study

The nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate tosylate have been carried out with a number of nucleophiles to study the possible attack of nucleophiles at C1, C2 or C3 positions. The regioselectivity and reactivity of both the substrates i.e. epoxide tosylate 1 and the corresponding cyclic sulfate 2 have been compared and established that under similar conditions cyclic sulfate counterpart shows better regioselectivity and better reactivity than the corresponding epoxide.