136465-99-1

Basic information

• Product Name: QUINALDIC ACID SUCCINIMIDE ESTER
• Synonyms: QUINALDIC ACID SUCCINIMIDE ESTER;N-(2-QUINOLYLCARBONYLOXY) SUCCINIMIDE;1-((2-quinolinyl-carbonyl)oxy)-2,5-pyrrolidinedione
• CAS NO: 136465-99-1
• Molecular Formula: C₁₄H₁₀N₂O₄
• Molecular Weight: 270.24
• EINECS: 418-630-3
• Mol File: 136465-99-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 190-192 °C(Solv: ethanol (64-17-5))
• Boiling Point: 453.2°Cat760mmHg
• Flash Point: 227.9°C
• Appearance: /
• Density: 1.46g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.676
• PKA: -0.18±0.48(Predicted)
• CAS DataBase Reference: QUINALDIC ACID SUCCINIMIDE ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: QUINALDIC ACID SUCCINIMIDE ESTER(136465-99-1)
• EPA Substance Registry System: QUINALDIC ACID SUCCINIMIDE ESTER(136465-99-1)

Safety Data

• Hazard Codes: Xi
• Statements: 41-43
• Safety Statements: 24-26-37/39
• Hazardous Substances Data: 136465-99-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H10N2O4/c17-12-7-8-13(18)16(12)20-14(19)11-6-5-9-3-1-2-4-10(9)15-11/h1-6H,7-8H2

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 93-10-7 quinoline-2-carboxylic acid 

Downstream Products

• 143224-34-4 [1S-[1R*(R*),2S*]]-N₁[3-[[[(1,1-dimethylethyl)amino]carbonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide 
• 115732-19-9 (R)-3-Phenyl-2-[(quinoline-2-carbonyl)-amino]-propionic acid 
• 127779-20-8 Saquinavir 
• 136465-98-0 (2S)-2-[(quinoline-2-carbonyl)-amino]-succinamic acid 
• 143224-34-4 Telinavir 
• 143224-34-4 (S)-N¹-[(1S,2S)-1-Benzyl-3-(3-tert-butyl-1-isobutyl-ureido)-2-hydroxy-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide 
• 146572-44-3 2(S)-[3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]-2(R)-hydroxy-4-phenylbutyl]-N-tert.butyl-1(R)-cyclohexanecarboxamide 

Relevant articles and documents

Expanding the scope of the elpaN-type library: Glucose-derived bis(pyridine-2-carboxamide) ligands (elpaN-Py) for molybdenum-catalyzed asymmetric allylic alkylations

The elpaN-Py family of ligands, which represents a subset of the elpaN-type library based on d-glucose, is described. The ligands are structural analogs of the privileged bis(pyridine-2-carboxamides) derived from trans-1,2- diaminocyclohexane, and differ

Synthesis of the HIV-proteinase inhibitor Saquinavir: A challenge for process research

The task of process research, namely developing efficient, economically and technically as well as ecologically feasible syntheses in time, is demonstrated on the HIV-proteinase inhibitor Saquinavir (1), a complex molecule comprising six stereo-centres. Based on the first 26-step research synthesis furnishing a 10% overall yield, process research established a new, short 11-step synthesis affording a 50% overall yield.