136505-41-4

Upstream product

• 138923-10-1 2-azido-4,6-O-benzylidene-2-deoxyl-1-O-tert-butyldimethylsilyl-β-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 153094-00-9 tert-Butyldimethylsilyl 2-azido-6-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 86520-63-0 2,3,4,6-tetra-O-acetyl-α-galactopyranosyl trichloroacetimidate 
• 99049-67-9 tert-Butyldimethylsilyl-2-azido-2-desoxy-β-D-glucopyranosid 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

GLYCOSYLATION WITH HIGHLY REACTIVE GLYCOSYL DONORS: EFFICIENCY OF THE INVERSE PROCEDURE

α-Fucosylation with the reactive trichloroacetimidate 1 as donor and disaccharides 2 and 4 as acceptors led to a remarkable increase in yield under "inverse conditions", i. e. addition of the donor to an acceptor/catalyst solution.Thus, acceptor/catalyst complex formation enforcing the generation of the glycosylation species in the vicinity of the acceptor is favored yielding building blocks for antigen determinant synthesis.

Regioselective lipase acylation as a useful tool for separation and selective protection of β-D-Gal(1→4)-D-GlcNAc and β-D-Gal(1→3)-D-GlcNAc disaccharides

Supported lipase from Candida antarctica (Chirazyme) was employed for a regioselective protection of the 2-azido derivatives 1 and 2, synthetic equivalents of β-D-Gal(1→3)-D-GlcNAc and β-D-Gal(1→4)-D-GlcNAc (N-acetyl lactosamine), respectively. The selectivity of the enzyme towards 1 and 2 was also exploited for an easy separation of the mixture of the two compounds obtained from a straightforward synthetic approach. Copyright (C) 2000 Elsevier Science Ltd.

Glycosyl Imidates, 65. Efficient Synthesis of the Lewis Antigen X (Lex) Family

tert-Butyldimethylsilyl 2-azido-4,6-O-benzylideneglucopyranoside 5 proved to be a versatile starting material for the synthesis of the Lex antigen family. 3-O-Fucosylation of 5, ensuing reductive benzylidene ring cleavage, and then 4-O-galactos

AN EFFICIENT SYNTHESIS OF THE LEWIS A (Lea) ANTIGEN PENTASACCHARIDE MOIETY

Starting material for the synthesis of Lewis A pentasaccharide (1) was azidoglucose derivative 2 which was readily transformed into the 3,4-O-unprotected derivative 3 of the 3-O-unprotected derivative 5, respectively.Reaction of 3 and O-galactosyltrichlor