1365265-70-8Relevant articles and documents
A focus on the asymmetric synthesis of a novel threo-β-benzyl-β- hydroxy aspartate analogue
Mekki, Sofiane,Bellahouel, Salima,Vanthuyne, Nicolas,Rolland, Marc,Derdour, Aicha,Martinez, Jean,Vignes, Michel,Rolland, Valerie
experimental part, p. 94 - 99 (2012/05/20)
Considering the biological activity of β-alkyl-β-hydroxyaspartate derivatives as potent blockers of glutamate transporters (EAATs) impacting on glutamatergic synapses activity, we have developed a concise, asymmetric synthesis of enantiomerically pure thr