1366097-14-4

Upstream product

• 85070-48-0 2-fluoro-3-chlorobenzaldehyde 
• 392332-35-3 6-chloro-2-oxindole 
• 1309685-88-8 tert-butyl[2-(3-methoxy-4-nitrophenoxy)ethoxy]dimethylsilane 
• 1309685-87-7 4-[2-(tert-butyldimethylsilanyloxy)ethoxy]-2-methoxyphenylamine 
• 1309685-95-7 (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carboxylic acid trifluoroacetic acid 
• 1309685-92-4 rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid tert-butyl ester 
• 1219086-34-6 2-[(E)-(3,3-dimethylbutylidene)amino]acetic acid tert-butyl ester 
• 897365-76-3 (3E/Z)-6-chloro-3-(3-chloro-2-fluorobenzylidene)-1,3-dihydro-2H-indol-2-one 
• 16292-95-8 4-nitro-3-methoxyphenol 
• 448-19-1 4-fluoro-2-methoxy-1-nitrobenzene 
• 50-00-0 formaldehyd 
• 1366097-82-6 (2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid {4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-2-methoxy-phenyl}-amide 
• 2987-16-8 3,3-dimethylbutyrylaldehyde 

Relevant academic research and scientific papers

Substituted Spiro[3H-Indole-3,6'(5'H)-[1H]Pyrrolo[1,2c]Imidazole-1',2(1H,2'H)-diones

There are provided compounds of the formula wherein X, Y, R1, R1′, R2, R2′, R3, R4, R5 and R6 are as described herein and enantiomers or a pharmaceutically acceptable salt or ester thereof. The compounds are useful as anticancer agents.