1366407-37-5

Basic information

• Product Name: 1-[2-(4-fluorophenyl)pyridin-4-yl]ethanone
• Synonyms: 1-[2-(4-fluorophenyl)pyridin-4-yl]ethanone
• CAS NO: 1366407-37-5
• Molecular Weight: 215.227
• Mol File: 1366407-37-5.mol

Chemical Properties

• CAS DataBase Reference: 1-[2-(4-fluorophenyl)pyridin-4-yl]ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(4-fluorophenyl)pyridin-4-yl]ethanone(1366407-37-5)
• EPA Substance Registry System: 1-[2-(4-fluorophenyl)pyridin-4-yl]ethanone(1366407-37-5)

Safety Data

• Hazardous Substances Data: 1366407-37-5(Hazardous Substances Data)

Upstream product

• 58861-53-3 4-fluorophenylpyridine 
• 122-51-0 orthoformic acid triethyl ester 
• 1765-93-1 4-fluoroboronic acid 
• 111043-06-2 1-(2-bromo-4-pyridinyl)ethanone 
• 656257-69-1 2-bromo-N-methyl-N-(methyloxy)-4-pyridinecarboxamide 
• 66572-56-3 2-bromoisonicotinic acid 
• 1214385-22-4 2-(4-fluorophenyl)pyridine-4-carbonitrile 
• 75-16-1 methylmagnesium bromide 
• 33252-30-1 2-chloro-4-pyridinenitrile 

Downstream Products

• 1366405-88-0 N-cyclobutyl-N-{1-[2-(4-fluorophenyl)pyridin-4-yl]ethyl}-1-methyl-1H-imidazole-4-carboxamide 
• 1366407-35-3 N-{1-[2-(4-fluorophenyl)pyridin-4-yl]ethyl}cyclobutaneamine 

Relevant articles and documents

Iron-Catalyzed Minisci Type Acetylation of N-Heteroarenes Mediated by CH(OEt)3/TBHP

Iron-catalyzed acetylation of electron deficient N-heteroarenes has been reported using triethylorthoformate as robust and inexpensive acetyl source. This new method is successfully applied for the acetylation of quinolines, isoquinoline, quinoxalines, arylpyridines, bipyridines, and benzothiazole.

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.

GLYCINE TRANSPORTER INHIBITING SUBSTANCES

The present invention aims to provide novel compounds of formula [I] or pharmaceutically acceptable salts thereof that are based on a glycine uptake inhibiting action and which are useful in the prevention or treatment of such diseases as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, posttraumatic stress disorder, specific phobia, acute stress disorder, etc.), depression, drug addiction, spasm, tremor, pain, and sleep disorder: