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58861-53-3

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58861-53-3 Usage

General Description

2-(4-Fluorophenyl)pyridine is a chemical compound that contains both pyridine and fluorophenyl functional groups. Pyridines are aromatic, six-membered rings that consist of five carbon atoms and one nitrogen atom and are fundamental elements in numerous pharmaceuticals and natural products. On the other hand, a fluorophenyl group relates to a phenyl group (which is basically a version of benzene) that has a fluorine atom attached to it. 2-(4-Fluorophenyl)pyridine, 2-(4-Fluorophenyl)pyridine, is used in advanced organic chemistry, usually as an intermediate in the synthesis of more complex molecules. Its precise properties such as melting point, boiling point, and density may vary based on certain conditions or forms, and proper safety and handling measures should be followed to prevent exposure and potential risks.

Check Digit Verification of cas no

The CAS Registry Mumber 58861-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,8,6 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 58861-53:
(7*5)+(6*8)+(5*8)+(4*6)+(3*1)+(2*5)+(1*3)=163
163 % 10 = 3
So 58861-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H8FN/c12-10-6-4-9(5-7-10)11-3-1-2-8-13-11/h1-8H

58861-53-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-Fluorophenyl)pyridine

1.2 Other means of identification

Product number -
Other names 2-(p-fluorophenyl)pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58861-53-3 SDS

58861-53-3Relevant articles and documents

Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki–Miyaura Cross-Coupling on a Thermally Stable CO-RM

Ward, Jonathan S.,Bray, Joshua T. W.,Aucott, Benjamin J.,Wagner, Conrad,Pridmore, Natalie E.,Whitwood, Adrian C.,Moir, James W. B.,Lynam, Jason M.,Fairlamb, Ian J. S.

, p. 5044 - 5051 (2016)

A new class of carbon monoxide-releasing molecules (CO-RMs) are reported based on a previously known tetracarbonyl phenylpyridine manganese(I) motif. A pre-functionalized CO-RM undergoes a direct Pd-catalysed Suzuki–Miyaura cross-coupling with phenylboronic acid to give a π-extended three-ring CO-RM. Cross-coupling conditions were modified to allow coupling of a morpholine-containing boronic acid on to a CO-RM, introducing drug-like functionality. An LED system was used to facilitate controlled CO-release. Irradiation using an LED (400 nm or 365 nm) gives rise to faster CO-release, with lower overall input power than traditional use of a TLC lamp (365 nm), as measured by an assay based on the conversion of deoxymyoglobin to carbonmonoxymyoglobin.

Nickel-Catalyzed Reductive 2-Pyridination of Aryl Iodides with Difluoromethyl 2-Pyridyl Sulfone

Miao, Wenjun,Ni, Chuanfa,Xiao, Pan,Jia, Rulong,Zhang, Wei,Hu, Jinbo

supporting information, p. 711 - 715 (2021/01/26)

A novel nickel-catalyzed reductive cross-coupling between aryl iodides and difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H) enables C(sp2)-C(sp2) bond formation through selective C(sp2)-S bond cleavage, which demonstrates the new reactivity of 2-PySO2CF2H reagent. This method employs readily available nickel catalyst and sulfones as cross-electrophile coupling partners, providing facile access to biaryls under mild reaction conditions without pregeneration of arylmetal reagents.

Access to Branched Allylarenes via Rhodium(III)-Catalyzed C-H Allylation of (Hetero)arenes with 2-Methylidenetrimethylene Carbonate

Zhang, Shang-Shi,Zheng, Yi-Chuan,Zhang, Zi-Wu,Chen, Shao-Yong,Xie, Hui,Shu, Bing,Song, Jia-Lin,Liu, Yan-Zhi,Zeng, Yao-Fu,Zhang, Luyong

supporting information, p. 5719 - 5723 (2021/08/16)

A rhodium(III)-catalyzed C-H allylation of (hetero)arenes by using 2-methylidenetrimethylene carbonate as an efficient allylic source has been developed for the first time. Five different directing groups including oxime, N-nitroso, purine, pyridine, and pyrimidine were compatible, delivering various branched allylarenes bearing an allylic hydroxyl group in moderate to excellent yields.

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