13669-62-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-6-methoxy-quinoline-3-carbonitrile is used as an intermediate compound for the synthesis of various pharmaceutical drugs. Its unique structure and reactivity make it a valuable building block in the development of new medications.
Used in Chemical Reactions:
4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE is used as a reactant in various chemical reactions, taking advantage of its nitrile and chloro groups to form new chemical entities. Its versatility in reactions contributes to the synthesis of a wide range of products in the chemical industry.
Used in Research and Development:
4-Chloro-6-methoxy-quinoline-3-carbonitrile is employed as a research compound in academic and industrial laboratories. Its unique properties make it an interesting subject for studying the effects of different functional groups on the reactivity and properties of quinoline-based compounds. This research can lead to the discovery of new applications and uses for 4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE in various fields.

InChI:InChI=1/C11H7ClN2O/c1-15-8-2-3-10-9(4-8)11(12)7(5-13)6-14-10/h2-4,6H,1H3

Upstream product

• 394-31-0 2-amino-5-hydroxybenzoic acid 
• 13669-61-9 4-hydroxy-6-methoxyquinoline-3-carbonitrile 
• 872714-51-7 4-bromo-6-methoxy-quinoline-3-carboxylic acid 
• 872714-50-6 4-bromo-6-methoxy-quinoline-3-carboxylic acid ethyl ester 
• 77156-78-6 ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate 
• 83507-70-4 diethyl 2-(((4-methoxyphenyl)amino)methylene)malonate 
• 104-94-9 4-methoxy-aniline 
• 476193-93-8 4-chloro-6-methoxy-quinoline-3-carboxylic acid amide 
• 872714-53-9 (E)-methyl 2-(((dimethylamino)methylene)amino)-5-methoxybenzoate 
• 2475-80-1 methyl 2-amino-5-methoxybenzoate 
• 423180-88-5 6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile 

Downstream Products

• 872714-54-0 4-ethenyl-6-(methyloxy)-3-quinolinecarbonitrile 
• 1598416-84-2 6-methoxy-4-(2-(4-(4-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598416-85-3 4-(2-(4-(4-hydroxy-3-methoxybenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-86-4 4-(2-(4-(4-fluoro-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-87-5 6-methoxy-4-(2-(4-(3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598416-88-6 4-(2-(4-(2-fluoro-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-92-2 4-(2-(4-(3-fluoro-4-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-93-3 N-(1-(2-(3-cyano-6-methoxyquinolin-4-yl)ethyl)piperidin-4-yl)-3-fluoro-4-nitrobenzamide 
• 1598416-96-6 4-(2-(4-(4-chloro-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-69-3 N-(8-(2-(3-cyano-6-methoxyquinolin-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methylbenzenesulfonamide 
• 1598416-97-7 4-(2-(4-(2-hydroxy-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-98-8 4-(2-(4-(4-hydroxy-3-methoxy-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-99-9 6-methoxy-4-(2-(4-(4-methyl-3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598417-02-7 6-methoxy-4-(2-(4-(4-methoxy-3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 

Relevant academic research and scientific papers

Hetero-aromatic compound and its use in medicine

The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.

INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present invention relates to compounds which specifically inhibit bacterial DNA Gyrase and can be used for the treatment of respiratory tract infections.

ANTIBACTERIAL AGENTS

Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.

Synthesis and structure-activity relationships of 3-cyano-4(phenoxyanilino)quinolines as MEK (MAPKK) inhibitors

A series of 3-cyano-4-(phenoxyanilino)cyanoquinolines has been prepared as MEK (MAP kinase kinase) inhibitors. The best activity is seen with alkoxy groups at both the 6- and 7-positions. The lead compounds show low nanomolar IC50's against MAP kinase kinase, and have potent inhibitory activity in tumor cells. (C) 2000 Elsevier Science Ltd.