13669-62-0

Basic information

• Product Name: 4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE
• Synonyms: 4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE ;4-Chloro-6-methoxy-quinoline-3-c;3-Quinolinecarbonitrile, 4-chloro-6-Methoxy-;4-chloro-6-methoxy-3-Quinolinecarbonitrile
• CAS NO: 13669-62-0
• Molecular Formula: C₁₁H₇ClN₂O
• Molecular Weight: 218.63908
• Product Categories: Quinoline&Isoquinoline
• Mol File: 13669-62-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 385.3 °C at 760 mmHg
• Flash Point: 186.8 °C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 3.84E-06mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.33±0.27(Predicted)
• CAS DataBase Reference: 4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE(13669-62-0)
• EPA Substance Registry System: 4-CHLORO-6-METHOXY-QUINOLINE-3-CARBONITRILE(13669-62-0)

Safety Data

• Hazardous Substances Data: 13669-62-0(Hazardous Substances Data)

Usage

General Description

4-Chloro-6-methoxy-quinoline-3-carbonitrile is a specialized chemical compound known for its usage in the medical and pharmaceutical industries due to quinoline's distinctive characteristics. The nitrile group (-CN) and chloro groups additionally incorporated in its structure enhance its reactive capability, making it ideal for use in various chemical reactions. It belongs to the class of organochlorines, which means it contains carbon-chlorine bonds. Its methoxy group (-OCH3) facilitates its solubility in organic solvents. This chemical compound is usually handled and stored in controlled environments due to its possible harmful effects when in contact with skin or if ingested or inhaled.

InChI:InChI=1/C11H7ClN2O/c1-15-8-2-3-10-9(4-8)11(12)7(5-13)6-14-10/h2-4,6H,1H3

Upstream product

• 394-31-0 2-amino-5-hydroxybenzoic acid 
• 13669-61-9 4-hydroxy-6-methoxyquinoline-3-carbonitrile 
• 872714-51-7 4-bromo-6-methoxy-quinoline-3-carboxylic acid 
• 872714-50-6 4-bromo-6-methoxy-quinoline-3-carboxylic acid ethyl ester 
• 77156-78-6 ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate 
• 83507-70-4 diethyl 2-(((4-methoxyphenyl)amino)methylene)malonate 
• 104-94-9 4-methoxy-aniline 
• 476193-93-8 4-chloro-6-methoxy-quinoline-3-carboxylic acid amide 
• 872714-53-9 (E)-methyl 2-(((dimethylamino)methylene)amino)-5-methoxybenzoate 
• 2475-80-1 methyl 2-amino-5-methoxybenzoate 
• 423180-88-5 6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile 

Downstream Products

• 1598416-84-2 6-methoxy-4-(2-(4-(4-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598416-85-3 4-(2-(4-(4-hydroxy-3-methoxybenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-86-4 4-(2-(4-(4-fluoro-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-87-5 6-methoxy-4-(2-(4-(3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598416-88-6 4-(2-(4-(2-fluoro-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-92-2 4-(2-(4-(3-fluoro-4-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-93-3 N-(1-(2-(3-cyano-6-methoxyquinolin-4-yl)ethyl)piperidin-4-yl)-3-fluoro-4-nitrobenzamide 
• 1598416-96-6 4-(2-(4-(4-chloro-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-69-3 N-(8-(2-(3-cyano-6-methoxyquinolin-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methylbenzenesulfonamide 
• 1598416-97-7 4-(2-(4-(2-hydroxy-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-98-8 4-(2-(4-(4-hydroxy-3-methoxy-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 
• 1598416-99-9 6-methoxy-4-(2-(4-(4-methyl-3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598417-02-7 6-methoxy-4-(2-(4-(4-methoxy-3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile 
• 1598417-36-7 4-(2-(4-(4-(dimethylamino)-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile 

Relevant articles and documents

Hetero-aromatic compound and its use in medicine

The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.

ANTIBACTERIAL AGENTS

Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.