13673-63-7

Usage

Chemical Properties

light brown needles

InChI:InChI=1/C8H7NOS/c1-9-6-4-2-3-5-7(6)10-8(9)11/h2-5H,1H3

Upstream product

• 13673-62-6 2-methylsulfanyl-benzoxazole 
• 80-48-8 methyl p-toluene sulfonate 
• 74-88-4 methyl iodide 
• 21892-80-8 3-methylbenzo[d]oxazol-2(3H)-one 
• 463-71-8 thiophosgene 
• 611-24-5 o-(N-methylamino)phenol 
• 2382-96-9 benzo[d]oxazole-2-(3H)-thione 
• 77-78-1 dimethyl sulfate 
• 59-49-4 2-Benzoxazolinone 
• 616-38-6 carbonic acid dimethyl ester 
• 2382-96-9 2-sulfanyl-1,3-benzoxazole 
• 76088-27-2 Triphenyl-(2-thioxo-benzooxazol-3-ylmethyl)-phosphonium; chloride 
• 50-00-0 formaldehyd 

Downstream Products

• 32353-07-4 3-Butyl-1-(2-hydroxy-phenyl)-1-methyl-thiourea 
• 7783-06-4 hydrogen sulfide 
• 15719-64-9 methylammonium carbonate 
• 611-24-5 o-(N-methylamino)phenol 
• 615-18-9 2-chloro-1,3-benzoxazole 
• 74-87-3 methylene chloride 

Relevant academic research and scientific papers

SH-methylation of SH-containing heterocycles with dimethyl carbonate via phase-transfer catalytic reaction

A reaction of SH-containing heterocycles with dimethyl carbonate (DMC) in the presence of K2CO3 and tetrabutylammonium bromide (Bu4NBr) gave heteroaryl methyl thioethers in 44-93% yields. The reaction was carried out under mild conditions. This method provided a useful synthetic method for preparation of various heteroaryl methyl thioethers without the use of toxic methylic halides or dimethyl sulfate.

Ionic liquids - Promoted S-methylation of thiols utilizing dimethyl carbonate

Convenient and efficient S-methylation of mercaptans or thiophenols occurs with dimethyl carbonate (DMC) in room temperature ionic liquids (RTILs) [Bmim]Cl. [Bmim]Cl can be recycled in four subsequent runs with only a gradual decrease in activity. A possible mechanism of this transformation is also discussed. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor & Francis Group, LLC.

MOLECULAR ADDUCTS BETWEEN IODINE AND SOME BENZAZOLE-2-THIONE AND -2-SELONE DERIVATIVES

Spectrophotometric studies of adducts obtained by reacting molecular iodine and some benzazole-2-thione and -2-selone derivatives have been carried out in CH2Cl2 solutions.The termodynamic and spectral characteristics of these complexes have been determined.Except for benzoxazole-2-selone and 3-methylbenzthiazole-2-selone, at least one isosbestic point has been found in the spectra of all the compounds, indicating the formation of 1:1 molecular adduct.This model, employed for the calculation of the stability constants, fits the experimental data well in all cases.A non-linear least-squares method has been used for the calculation, and attention has been taken in selecting the experimental points to improve the reliability of the K and ε values.

Synthesis of 3-Substitued Benzoxazoline-2-thiones

Several methods for the preparation of 3-substitued benzoxazoline-2-hiones (1) were examined.Method B via the thiation of 3-substitued benzoxazoline-2-one (5) with phosphorus pentasulfide was found to be applicable to the preparation of most analogs of 1, with a few expections.Method C via the cyclization of 2-(alkylamino)phenol (7) with potassium O-methyldithiocarbonate was suitable for the preparation of analogs with a group sensitive to high temperature of with an aryl- (including aromatic heterocyclic ring) methyl group.In addition, the reaction of benzoxazoline-2-thione (2) with acetals such as 1-ethoxyisochroman, 2-ethoxytetrahydrofuran, and ethoxytetraydropyran, or with Michael acceptors such as 2,3-dihydrofuran and 2H-3,4-dihydropyran, gave 3-substitued benzoxazoline-2-thione (1d-f).

BENZOXAZOLINONES. II. SYNTHESIS OF 3-VINYLBENZOXAZOLINONES AND 3-VINYLBENZOXAZOLINETHIONE

A method has been developed for obtaining 3-vinylbenzoxazolinones and 3-vinylbenzoxazolinethione.It has been shown that it is also possible to obtain 3-methylbenzoxazolinethione by this method in good yield (76percent).