136749-73-0 Usage
Chemical structure
Dioxetane derivative with a chloromethyl and phenyl group attached to the oxygen atoms
The core structure is a four-membered ring containing two oxygen atoms, with a chlorine atom and a phenyl group attached to the oxygen atoms.
Application
Reagent in synthetic organic chemistry
It is used in the synthesis of various pharmaceuticals and complex organic molecules.
Potential use
Chemiluminescence assays and production of chemiluminescent compounds
It has been studied for its potential application in chemiluminescence assays and as a precursor for the production of chemiluminescent compounds.
Hazardous nature
Should be handled with care and in accordance with proper safety guidelines
Due to its hazardous nature, it is crucial to follow safety protocols and guidelines when working with 1,2-Dioxetane, 3-(chloromethyl)-3-phenyl-.
Check Digit Verification of cas no
The CAS Registry Mumber 136749-73-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,7,4 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 136749-73:
(8*1)+(7*3)+(6*6)+(5*7)+(4*4)+(3*9)+(2*7)+(1*3)=160
160 % 10 = 0
So 136749-73-0 is a valid CAS Registry Number.
136749-73-0Relevant academic research and scientific papers
Novel Transformations of 1,2-Dioxetanes: β-Hydroxy Ethers by Addition of Alkyllithium Reagents
Adam, Waldemar,Heil, Markus
, p. 235 - 241 (2007/10/02)
The reaction of 1,2-dioxetanes with alkyllithium reagents was investigated.The 3,3-disubstituted dioxetanes 2a,d and their halogen-substituted analogues 2b,c, which were used as probes to differentiate between the mechanistic alternatives (SN2 reactivity vs. single-electron transfer), reacted with n-BuLi to afford the β-hydroxy ethers 3a-d.Additionally, the epoxide 4 was obtained from dioxetanes 2b,c.The epoxide 5 and a small amount of acetophenone were found in the reaction of dioxetane 2c with triphenylmethyllithium, but only the minor part of the dioxetane-derived products could be identified.The observation of the epoxides 4 and 5 led to the mechanistic conclusion that nucleophilic attack (SN2 reactivity) is the most prominent process in this reaction.Key Words: Dioxetanes / Single electron transfer vs. nucleophilic attack / Ethers, β-hydroxy / Alkyllithium reagents
