1367928-40-2

Upstream product

• 4869-59-4 3-mercapto benzoic acid 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 1097039-33-2 3-((4-chlorobenzyl)sulfonyl)benzoic acid 
• 1479965-70-2 3-((4-chlorobenzyl)sulfinyl)benzoic acid 
• 1616241-54-3 N-(4-cyanophenyl)-3-((4-chlorobenzyl)sulfinyl)benzamide 
• 1616241-49-6 3-((4-chlorobenzyl)sulfonyl)-N-(6-chloropyridazin-3-yl)benzamide 
• 1616241-46-3 3-((4-chlorobenzyl)sulfonyl)-N-(5-cyanopyridin-2-yl)benzamide 
• 1616241-43-0 3-((4-chlorobenzyl)sulfonyl)-N-(5-chloropyridin-2-yl)benzamide 
• 1616241-41-8 3-((4-chlorobenzyl)sulfonyl)-N-(4-chlorophenyl)benzamide 

Relevant academic research and scientific papers

Design and evaluation of 3-(benzylthio)benzamide derivatives as potent and selective SIRT2 inhibitors

Inhibitors of sirtuin-2 (SIRT2) deacetylase have been shown to be protective in various models of Huntington's disease (HD) by decreasing polyglutamine aggregation, a hallmark of HD pathology. The present study was directed at optimizing the potency of SI

BENZAMIDE COMPOUNDS AND RELATED METHODS OF USE

Benzamide compounds and derivatives thereof, as can be used for selective inhibition of the SIRT2 enzyme and/or therapeutic use in the treatment of Huntington's disease.