13680-12-1Relevant academic research and scientific papers
Fabrication of an amyloid fibril-palladium nanocomposite: A sustainable catalyst for C-H activation and the electrooxidation of ethanol
Jayarajan, Ramasamy,Kumar, Rakesh,Gupta, Jagriti,Dev, Gayathri,Kadu, Pradeep,Chatterjee, Debdeep,Bahadur, Dhirendra,Maiti, Debabrata,Maji, Samir K.
supporting information, p. 4486 - 4493 (2019/03/06)
Amyloids are highly ordered nanofibrils and their tensile strength is similar to that of steel, which makes them resistant to extreme pH and temperature. Based on this rationale, we demonstrate a facile synthesis of palladium, copper, platinum, gold and silver nanocomposites using α-Synuclein (α-Syn) fibrils as a template. We showed that an α-Syn-fibril-palladium nanoparticles (α-Syn-PdNPs) composite can be used as a heterogeneous catalyst in C-H bond activation and the electrooxidation of ethanol. The study demonstrated α-Syn-PdNPs to be a superior heterogeneous catalyst for the synthesis of pharmaceutically valuable benzofuran, naphthofuran, coumarin and N-arylindole via C-H activation. Further, the electrooxidation of ethanol using α-Syn-PdNPs displayed an electrochemically active surface area of 160.6 m2 g-1, which is much higher than the previously reported values for supported Pd nanocomposites.
Palladium-catalyzed synthesis of benzofurans and coumarins from phenols and olefins
Sharma, Upendra,Naveen, Togati,Maji, Arun,Manna, Srimanta,Maiti, Debabrata
supporting information, p. 12669 - 12673 (2013/12/04)
Triple C-H functionalization: Palladium-catalyzed synthesis of benzofurans and coumarins by reacting phenols and unactivated olefins is described. The reaction comprises sequential C-H functionalization and shows diverse functional group compatibility. Preliminary mechanistic studies shed light into the possible mechanisms. Copyright
BENZOFURANS AS POTASSIUM ION CHANNEL MODULATORS
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Page/Page column 28-29, (2008/06/13)
The present invention is directed to compounds of Formula I: that are potassium channel modulators and pharmaceutical compositions thereof. The present invention is further directed to methods of treatment using the compounds and pharmaceutical compositions of the invention. The present invention is still further directed to synthetic processes for producing the compounds of the invention.
