136924-91-9

Upstream product

• 117294-21-0 8-bromo-2-tetralone 
• 136924-90-8 (-)-(2S)-8-bromo-N-<(S)-α-methylbenzyl>-2-aminotetralin 
• 55116-09-1 2-bromophenylacetyl chloride 
• 136905-89-0 (-)-8-bromo-N-<(S)-α-methylbenzyl>-2(S)-propionamidotetralin 

Downstream Products

• 136924-93-1 (-)-2-carbomethoxy-N-<(S)-α-methylbenzyl>-N-propyl-8(S)-amino-6,7,8,9-tetrahydro-3H-benzindole 
• 149525-99-5 (-)-2-carbamoyl-N-<(S)-α-methylbenzyl>-N-propyl-8(S)-amino-6,7,8,9-tetrahydro-3H-benzindole 
• 136905-92-5 (-)-8-<(Z)-2-azido-3-methoxy-3-oxopropenyl>-N-<(S)-α-methylbenzyl>-N-propyl-2(S)-aminotetralin 
• 136924-92-0 (-)-8-formyl-N-<(S)-α-methylbenzyl>-N-propyl-2(S)-aminotetralin 

Relevant academic research and scientific papers

Novel 2-substituted tetrahydro-3H-benz[e]indolamines: Highly potent and selective agonists acting at the 5-HT(1A) receptor as possible anxiolytics and antidepressants

The synthesis of (+)-(R)-2-cyano-N,N-dipropyl-8-amino-6,7,8,9-tetrahydro- 3H-benz[e]indole [(R)-14, U92016A], a potent 5-HT(1A) agonist, and related analogs is described. In vitro binding studies show that the (R)-enantiomers of this series possess the hi