136905-89-0Relevant academic research and scientific papers
Novel 2-substituted tetrahydro-3H-benz[e]indolamines: Highly potent and selective agonists acting at the 5-HT(1A) receptor as possible anxiolytics and antidepressants
Romero,Leiby,McCall,Piercey,Smith,Han
, p. 2066 - 2074 (2007/10/02)
The synthesis of (+)-(R)-2-cyano-N,N-dipropyl-8-amino-6,7,8,9-tetrahydro- 3H-benz[e]indole [(R)-14, U92016A], a potent 5-HT(1A) agonist, and related analogs is described. In vitro binding studies show that the (R)-enantiomers of this series possess the hi
