1369424-04-3

Upstream product

• 735351-37-8 4-(4-fluoro-benzoylamino)benzoyl chloride 
• 72-14-0 Sulfathiazole 
• 54057-46-4 4-[(4-fluorobenzoyl)amino]benzoic acid 
• 172950-63-9 ethyl 4-(4-fluorobenzamido)benzoate 
• 403-43-0 4-fluorobenzoyl chloride 
• 456-22-4 4-Fluorobenzoic acid 

Relevant academic research and scientific papers

arone and amide compound and its preparation and use in medicine

The invention discloses a novel arone and arylamide compound represented by formula I, a cistrans isomer, physiologically acceptable salts, a solvate and a crystallizing form thereof, a preparation method of the compound, a medicine preparation containing the compound and clinical application of the compound in treating diseases related to protein tyrosine phosphatases 1B.

Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors

Fifteen novel sulfathiazole-related compounds were designed as PTP1B inhibitors based on a previously reported allosteric inhibitor (1) of PTP1B. These compounds were synthesized and evaluated against human recombinant PTP1B. Six compounds (3, 4, 8 and 14