735351-37-8Relevant articles and documents
Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors
Tang, Yan-Bo,Lu, Dianyun,Chen, Zheng,Hu, Chun,Yang, Ying,Tian, Jin-Ying,Ye, Fei,Wu, Li,Zhang, Zhong-Yin,Xiao, Zhiyan
, p. 2313 - 2318 (2013/05/09)
Fifteen novel sulfathiazole-related compounds were designed as PTP1B inhibitors based on a previously reported allosteric inhibitor (1) of PTP1B. These compounds were synthesized and evaluated against human recombinant PTP1B. Six compounds (3, 4, 8 and 14