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2-Aminobenzoic acid-5-sulfonamide, commonly known as sulfanilamide, is an organic compound that is part of the sulfonamide class of antibiotics. It features a benzene ring with both a sulfonamide group and an amino group attached, which gives it its antimicrobial properties.

137-65-5

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137-65-5 Usage

Uses

Used in Pharmaceutical Industry:
Sulfanilamide is utilized as an antimicrobial agent for the treatment of various bacterial infections. It functions by disrupting the synthesis of folic acid in bacteria, which is essential for their growth and proliferation.
Used in Treatment of Urinary Tract Infections:
Sulfanilamide is employed as a therapeutic agent for urinary tract infections, where its antimicrobial action helps to combat the bacterial infection causing the condition.
Used in Treatment of Burn Wounds:
In the context of burn wounds, sulfanilamide is used to prevent and treat bacterial infections that can occur in these compromised areas of the skin.
Used in Synthesis of Other Drugs:
Sulfanilamide also serves as a starting material in the pharmaceutical industry for the synthesis of other drugs, contributing to the development of a broader range of medicinal compounds.
Used in Dyes and Chemical Reactions:
Beyond its medicinal applications, sulfanilamide is used as a component in dyes and participates in various chemical reactions, highlighting its versatility in different industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 137-65-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 137-65:
(5*1)+(4*3)+(3*7)+(2*6)+(1*5)=55
55 % 10 = 5
So 137-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O4S/c8-6-2-1-4(14(9,12)13)3-5(6)7(10)11/h1-3H,8H2,(H,10,11)(H2,9,12,13)

137-65-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-5-sulfamoylbenzoic acid

1.2 Other means of identification

Product number -
Other names 2-Amino benzoic acid-5-sulfonamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:137-65-5 SDS

137-65-5Synthetic route

2-acetylamino-5-sulfamoyl-benzoic acid

2-acetylamino-5-sulfamoyl-benzoic acid

2-amino-5-sulfamoylbenzoic acid
137-65-5

2-amino-5-sulfamoylbenzoic acid

Conditions
ConditionsYield
With hydrogenchloride
2-hydroxyoxalylamino-5-sulfamoyl-benzoic acid

2-hydroxyoxalylamino-5-sulfamoyl-benzoic acid

2-amino-5-sulfamoylbenzoic acid
137-65-5

2-amino-5-sulfamoylbenzoic acid

Conditions
ConditionsYield
With sodium hydroxide
methanol
67-56-1

methanol

4-chloro-2-furfurylamino-5-sulfamoyl-benzoic acid
54-31-9

4-chloro-2-furfurylamino-5-sulfamoyl-benzoic acid

A

2-furfurylamino-5-sulfamoyl-benzoic acid
4818-85-3

2-furfurylamino-5-sulfamoyl-benzoic acid

B

2-amino-5-sulfamoylbenzoic acid
137-65-5

2-amino-5-sulfamoylbenzoic acid

C

4-chloro-5-sulfamoylanthranilic acid
3086-91-7

4-chloro-5-sulfamoylanthranilic acid

D

2-Amino-4-methoxy-5-sulfamoyl-benzoic acid

2-Amino-4-methoxy-5-sulfamoyl-benzoic acid

E

2-[(Furan-2-ylmethyl)-amino]-4-methoxy-5-sulfamoyl-benzoic acid

2-[(Furan-2-ylmethyl)-amino]-4-methoxy-5-sulfamoyl-benzoic acid

Conditions
ConditionsYield
at 30℃; for 0.166667h; Mechanism; Quantum yield; Irradiation;
N-[4-(aminosulfonyl)-2-methylphenyl]acetamide
252562-03-1

N-[4-(aminosulfonyl)-2-methylphenyl]acetamide

2-amino-5-sulfamoylbenzoic acid
137-65-5

2-amino-5-sulfamoylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous KMnO4
2: aqueous HCl
View Scheme

137-65-5Downstream Products

137-65-5Relevant academic research and scientific papers

Photolytic degradation of frusemide

Moore,Sithipitaks

, p. 489 - 493 (1983)

Irradiation with 365 nm u.v. light of frusemide (4-chloro-N-furfuryl-5-sulphamoyl-anthranilic acid) in methanol results primarily in photoreduction to N-furfuryl-5-sulphamoylanthranilic acid and photohydrolysis to 4-chloro-5-sulphamoylanthranilic acid (saluamine).

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