1370046-40-4

Basic information

• Product Name: 3-phenyl-5-(3,4,5,-tri-OCH₃-phenyl)-4,5-dihydro 1H-pyrazole-1-carbothioamide
• CAS NO: 1370046-40-4
• Molecular Weight: 371.46
• Mol File: 1370046-40-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 518.7±60.0 °C(Predicted)
• Density: 1.27±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 3-phenyl-5-(3,4,5,-tri-OCH₃-phenyl)-4,5-dihydro 1H-pyrazole-1-carbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-5-(3,4,5,-tri-OCH₃-phenyl)-4,5-dihydro 1H-pyrazole-1-carbothioamide(1370046-40-4)
• EPA Substance Registry System: 3-phenyl-5-(3,4,5,-tri-OCH₃-phenyl)-4,5-dihydro 1H-pyrazole-1-carbothioamide(1370046-40-4)

Safety Data

• Hazardous Substances Data: 1370046-40-4(Hazardous Substances Data)

Usage

General Description

3-phenyl-5-(3,4,5-tri-OCH3-phenyl)-4,5-dihydro 1H-pyrazole-1-carbothioamide is a chemical compound with a complex molecular structure. It contains a pyrazole ring, a thioamide functional group, and multiple phenyl rings with methoxy substituents. The compound is potentially important in the field of medicinal chemistry, as it may have biological activity or therapeutic potential. Its specific properties and potential uses would need to be determined through further research and testing.

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 127034-55-3 3,4,5-trimethoxychalcone 
• 79-19-6 thiosemicarbazide 
• 98-86-2 acetophenone 

Relevant articles and documents

Synthesis, spectroscopic characterization, in vitro cytotoxic and structure activity relationships of some mononuclear Ru(II) complexes

New mononuclear Ru(II) complexes [Ru(A)2(B)}2+, where A= 2,2'-bipyridine/1,10-phenanthroline and B= 3,4,5-tri-OCH3-DPC, 4-CH3-DPC, 4-N(CH3)2-DPC, 4-NO2-DPC, N-BITSZ, PTSZ and PINH, were prepared and characterized by spectroscopic methods. The in vitro cytotoxic activities of the complexes and their corresponding ligands were investigated against the human cancer TlyMPhocyte cell lines molt 4/c8 and CEM and the murine tumor leukemia cell line L1210, human promyelocytic leukemia cells (HL-60) and Bel-7402 liver cancer cells by MTT assay. The complexes [Ru(A)2(B)}2+ (A= 1,10-phenanthroline, B= 3,4,5-tri-OCH3-DPC) exerts rather more potent activities against all of these cell lines, especially for CEM and L1210. Ru complexes and structure-activity relationships and anticancer mechanisms are also discussed.