137005-61-9Relevant academic research and scientific papers
Highly enantio- and diastereoselective synthesis of α- trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst
Li, Peng,Chai, Zhuo,Zhao, Sheng-Li,Yang, Ying-Quan,Wang, Hai-Feng,Zheng, Chang-Wu,Cai, Yue-Peng,Zhao, Gang,Zhu, Shi-Zheng
supporting information; experimental part, p. 7369 - 7371 (2010/06/14)
The first enantioselective Michael addition of α-cyanoketones to α,β-unsaturated trifluoromethyl ketones using a novel piperazine-thiourea catalyst was described. The resulting α- trifluoromethyldihydropyrans were obtained in high yields and with up to 95
Dipeptide Side-Chain Chain Hydrophobic Interactions as Conformational Core for Chymotrypsin Inhibition
Sakamoto, Hiroshi,Shimohigashi, Yasuyuki,Ogawa, Tomohisa,Kawano, Keiichi,Ohno, Motonori
, p. 2519 - 2523 (2007/10/02)
A series of dipeptides with the sequence H-D-Leu-L-Phe-R denotes 4-phenylpiperidide, 4-phenylpiperazide, and their derivatives, have been synthesized to examine their ability to inhibit chymotrypsin.Dipeptide phenylpiperidide and phenylpiperazide inhibite
