137007-30-8Relevant articles and documents
An Efficient Synthesis of Hydroxyethylene Dipeptide Isosteres: The Core Unit of Potent HIV-1 Protease Inhibitors
Ghosh, Arun K.,McKee, Sean P.,Thompson, Wayne J.
, p. 6500 - 6503 (2007/10/02)
An efficient and stereocontrolled synthesis of hydroxyethylene dipeptide isosteres 1 from commercially available, optically pure D-mannose is described.This synthesis represents a practical and enantioselective entry to a range of other dipeptide isostere