137035-64-4

Upstream product

• 100-39-0 benzyl bromide 
• 80483-16-5 L-fucal 
• 53657-42-4 L-rhamnal 
• 34819-86-8 3,4-di-O-acetyl-6-deoxy-L-glucal 

Downstream Products

• 106988-71-0 4-O-acetyl-1,5-anhydro-3-O-benzyl-2,6-dideoxy-L-lyxo-hex-1-enitol 
• 136933-31-8 4-O-(4-O-acetyl-2,3,6-trideoxy-2-iodo-α-L-arabino-hexopyranosyl)-1,5-anhydro-3-O-benzyl-2,6-dideoxy-L-lyxo-hex-1-enitol 
• 136933-34-1 benzyl 3-azido-(3-O-benzyl-2,6-dideoxy-2-iodo-α-L-talopyranosyl)-2,3,6-trideoxy-α-L-threo-hex-2-enopyranoside 
• 136933-33-0 benzyl 4-O-(4-O-acetyl-3-O-benzyl-2,6-dideoxy-2-iodo-α-L-talopyranosyl)-3-azido-2,3,6-trideoxy-α-L-threo-hex-2-enopyranoside 
• 79080-88-9 3,4-di-O-benzyl-6-deoxy-α-L-mannopyranose 
• 78161-49-6 3,4-di-O-benzyl-L-rhamnopyranose 

Relevant academic research and scientific papers

MACROCYCLIC PICOLINAMIDES AS FUNGICIDES

The invention relates to macrocyclic picolinamides of Formula I and their use as fungicides.

Methods and compositions for the manufacture of C-3' and C-4' anthracycline antibiotics

The present invention discloses new and novel substituted anthracyclines with modified alkyl-aromatic ring substitutions on the C-3′ of the sugar moiety or modified or unmodified alkyl-aromatic ring substitutions at the C-4′ of the sugar moiety. It also d

Approaches to the C-B-A trisaccharide of dihydroaclacinomycin by extending the chain from either side

Selective benzylation of L-fucal (1) under phase-transfer conditions gave the 3- and 4-monoethers 2 and 3, respectively. Two routes, the 'tail' or the 'head' addition are presented, both leading to the target molecule 9, a mimic of the C-B-A trisaccharide component of dihydroaclacinomycin. Addition of glycals 2 and 3, respectively, to the acetylated glycal (7) of amicetose used as glycosyl donor gave the disaccharide glycals 6 and 8. Alternatively, glycosylation of the 4-acetate (4) of 2 with the benzyl hex-2-enopyranoside derivative 10 gave the disaccharide derivative 11. In the first case, the final glycosylation step involves the addition of 10 to disaccharide glycal 8. In the second procedure, the disaccharide alcohol 12 is obtained by O-deacetylation of 11, and serves as the glycosyl acceptor for glycal derivative 7 to give the C-B-A precursor trisaccharide derivative 9. Selective benzylation of L-fucal (1) under phase-transfer conditions gave the 3- and 4-monoethers 2 and 3, respectively. Two routes, the 'tail' or the 'head' addition are presented, both leading to the target molecule 9, a mimic of the C-B-A trisaccharide component of dihydroaclacinomycin. Addition of glycals 2 and 3, respectively, to the acetylated glycal (7) of amicetose used as glycosyl donor gave the disaccharide glycals 6 and 8. Alternatively, glycosylation of the 4-acetate (4) of 2 with the benzyl hex-2-enopyranoside derivative 10 gave the disaccharide derivative 11. In the first case, the final glycosylation step involves the addition of 10 to disaccharide glycal 8. In the second procedure, the disaccharide alcohol 12 is obtained by O-deacetylation of 11, and serves as the glycosyl acceptor for glycal derivative 7 to give the C-B-A precursor trisaccharide derivative 9.

SELECTIVER AUFBAU α-L-(1->4)-VERKNUEPFTER 2,6-DIDESOXY-OLIGOSACCHARIDE

The phase-transfer catalyzed benzylation of 1,5-anhydro-2,6-dideoxy-L-arabino-hex-1-enitol (L-rhamnal, 5) led to a mixture of 4- and 3-O-benzyl derivatives in the ratio of 2:1.By silylation, 5 was regiospecifically transformed into either the 3-O-tert-but