1370531-77-3

Basic information

• Product Name: C₃₀H₄₅N₃O₅
• Synonyms: C₃₀H₄₅N₃O₅
• CAS NO: 1370531-77-3
• Molecular Weight: 527.704
• Mol File: 1370531-77-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₀H₄₅N₃O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₀H₄₅N₃O₅(1370531-77-3)
• EPA Substance Registry System: C₃₀H₄₅N₃O₅(1370531-77-3)

Safety Data

• Hazardous Substances Data: 1370531-77-3(Hazardous Substances Data)

Upstream product

• 3218-02-8 cyclohexylmethylamine 
• 54699-42-2 N-cyclohexyl-N-cyclooctylidenamine 
• 1038694-95-9 C₂₁H₃₁NO₃ 
• 502-49-8 cycloactanone 
• 2971-79-1 isonipecotic acid methyl ester 

Relevant articles and documents

CB 1/2 dual agonists with 3-carbamoyl 2-pyridone derivatives as antipruritics: Reduction of CNS side effects by introducing polar functional groups

Our lead compound 1 showed high affinity for both CB1 and CB2 receptors, suggesting the possibility of inducing psychoactive side effects through the CB1 receptor in the brain. To solve this issue, polar functional groups were introduced at the 3-position of the pyridone core of compound 1 to find CB1/2 dual agonists such as 17 and 20 which did not show any CNS side effects.