1370731-53-5

Upstream product

• 13450-77-6 4-chlorohippuric acid 
• 300800-07-1 methyl 2-(4-chlorophenyl)-1,3-oxazole-4-carboxylate 
• 603-35-0 triphenylphosphine 
• 3848-36-0 4-chlorobenzaldoxime 
• 40546-41-6 ethyl-4-chlorobenzimidate hydrochloride 
• 104-88-1 4-chlorobenzaldehyde 
• 1333221-42-3 methyl 2-(4-chlorophenyl)-4,5-dihydro-1,3-oxazole-4-carboxylate 
• 71-43-2 benzene 
• 623-03-0 4-Cyanochlorobenzene 

Relevant academic research and scientific papers

Aryl-aryl coupling via palladium-catalyzed C-P/C-H bond cleavage

The first example of aryl-aryl coupling through palladium-catalyzed C-P/C-H bond cleavage with good functional group tolerance is disclosed. This work demonstrates the phosphines could be used as coupling partners in palladium-catalyzed aryl-aryl coupling

Synthesis of oxazoles from enamides via phenyliodine diacetate-mediated intramolecular oxidative cyclization

A group of functionalized oxazoles were synthesized in moderate to good yields from enamides via phenyliodine diacetate (PIDA)-mediated intramolecular cyclization. The main advantageous features of the present method include its broad substrate scope and the heavy-metal-free characteristic of the oxidative carbon-oxygen bond formation process.

Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C-H bond cleavage

The first palladium-catalyzed direct C5-arylation of azole-4-carboxylates with simple unactivated arenes through double C-H bond cleavage is realized. This protocol provided a straightforward access to diverse 5-arylsubstituted azole-4-carboxylic derivatives with good functional group tolerance. The Royal Society of Chemistry 2012.