137129-33-0

Upstream product

• 3731-51-9 2-(Aminomethyl)pyridine 
• 90-02-8 salicylaldehyde 
• 100-52-7 benzaldehyde 
• 88328-13-6 1-phenyl-N-(2-(pyridin-2-yl)methyl)methanimine 
• 7646-85-7 zinc(II) chloride 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 80767-78-8 {(2-Hydroxy-phenyl)-[(pyridin-2-ylmethyl)-amino]-methyl}-phosphonic acid 
• 63671-68-1 N-(2-pyridylmethyl)-2-hydroxybenzylamine 
• 205313-75-3 2-(((2-hydroxybenzyl)(pyridin-2-ylmethyl)amino)methyl)-4-nitrophenol 
• 123674-05-5 N,N-bis(2-hydroxybenzyl)-N-(2-pyridylmethyl)amine 
• 1401696-19-2 1-[N-(2-pyridylmethyl),N-(2-hydroxybenzyl)amino]-3-[N′-(2-hydroxybenzyl),N′-(4-methylbenzyl)amino]propan-2-ol 

Relevant academic research and scientific papers

Crystal structures of [Zn(SALIMP)(CH3CO2)] 2 and [Cu(SALIMP)Cl] with 2-[[(2-pyridinylmethyl) imino]methyl]phenol (HSALIMP) as a ligand

Two complexes [Zn(SALIMP)(CH3CO2)]2 (1) and [Cu(SALIMP)Cl] (2) are obtained by the reactions of zinc(II) and copper(II) salts with a tridentate Schiff base ligand 2-[[(2-pyridinylmethyl)imino]methyl] phenol (HSALIMP). Thei

Two multidentate ligands utilizing triazolyl, pyridinyl and phenolate groups as donors for constructing dinuclear copper(II) and iron(III) complexes: Syntheses, structures, and electrochemistry

Two multidentate ligands 2,2′-(1,1′-(pyridine-2,6-diylbis(methylene))bis(1H-1,2,3-triazole-4,1-diyl))bis(methylene)bis((pyridin-2-ylmethyl)azanediyl)bis(methylene)diphenol (H2LI) and N,N′-((1,1′-(pyridine-2,6-diylbis(methylene))bis(1H-1,2,3-triazole-4,1-diyl))bis(methylene))bis(1-(pyridin-2-yl)-N-(pyridin-2-ylmethyl)methanamine) (LII) containing triazolyl, phenolate and pyridinyl groups were prepared by click reaction between diazide and terminal alkynes in the presence of catalyst CuI. Both ligands were reacted with Cu2+and Fe3+salts to give three dinuclear complexes [LICu2](BPh4)2·2DMF (1), [LII(DMF)2Cu2](ClO4)4·H2O (2) and [LII(FeCl2)2](PF6)2(3). All complexes were characterized by IR, UV-Vis spectra and element analysis. X-ray analysis revealed that the Cu2+centers in complexes 1 and 2 adopted the distorted trigonal bipyramidal geometry, and the Fe3+center in complex 3 chose an octahedral geometry. In addition, the electrochemistry of complexes 1-3 was investigated.

Trans-keto* form detection in non photochromic N-salicylidene aminomethylpyridines

Five N-(5-chloro)salicylidene aminomethylpyridine derivatives were successfully synthesized and their structural and solid state optical properties analyzed. Yellow crystalline powders of CH2L3 and CH 2L3-4Cl pr

Two Schiff base ligands for distinguishing ZnII/CdII sensing - Effect of substituent on fluorescent sensing

Two Schiff base ligands (HL1, HL2) were conveniently synthesised by one-step condensation between pyridine 2-ylmethanamine and 3-ethoxy-2-hydroxybenzenaldhyde (for HL1) or salicylaldehyde (for HL2) as fluorescent sensors for distinguishing sensing of Zn2+ or Cd2+. Both of the two fluorescent sensors present very weak emission at 463 nm (for HL1) or 453 nm (for HL2). For HL1, upon addition of Zn2+, the fluorescence intensity of HL1 enhanced and gradually red shifted to 493 nm with a green emission while addition of Cd2+ only induced enhancement of fluorescent intensity at 463 nm. For HL2, only addition of Zn2+ induced enhancement of fluorescence intensity, presenting a high Zn2+/Cd2+ selectivity. A Zn2+-induced red shift in fluorescent spectra of HL1 could be attributed to twisted intramolecular charge transfer (TICT) from the interaction between the Zn2+ ion and in situ formed ligand L1′ with the twisted structure in compound 1, which is absent in compound 2. The Zn2+/Cd2+ selectivity of fluorescent response for HL2 correlates with the Cd-HL2 and Zn-HL2 coordination bond distances. Obviously, introduction of ethoxyl groups onto the benzene ring as an electron-donating group facilitates the Zn-induced in situ dimerization of HL1 into new ligand L1′ with a twisted molecular structure, further resulting in a red shift of the fluorescence spectra.

DNA binding and nuclease activity of copper(II) complexes of tridentate ligands

Two copper(II) complexes, 1 and 2 with L1 and L2 [L1 = 2-hydroxybenzyl(2-(pyridin-2-yl)ethylamine); L2 = 2-hydroxybenzyl(2-(pyridin-2-yl)methylamine)] ligands, respectively, have been synthesized and characteriz

A novel pentacoordinated dioxovanadium(v) salicylaldiminate: Solvent specific crystallization of dimorphs with contrasting coordination geometries, ligand conformations and supramolecular architectures

The reaction of the tridentate salicylaldimine of 2-picolylamine, C 6H4(OH)CHNCH2C5H4N (HL), with bis(acetylacetonato)oxovanadium(IV) at room temperature under oxygen (or with VOSO4·5H2O plus H2O2) furnished crystalline greenish-yellow α-VO2(L) and green β-VO2(L) from methanol (or ethanol) and acetonitrile (or dichloromethane), respectively. The dimorphs give rise to the same solution species as revealed by spectroscopic data (UV/Vis, 1H and 51V NMR). Both forms react with 3,5-bis(tert-butyl)catechol (H 2dbcat) furnishing the known pseudooctahedral complex VO(L)(dbcat). In the α form the V(L) fragment is planar and the VO3N 2 coordination sphere is distorted trigonal bipyramidal (τ = 0.55) with the two oxo oxygen atoms and the azomethine nitrogen atom defining the trigonal plane. In β-VO2(L) the V(L) moiety, like that in VO(L)(dbcat), is not planar but consists of two planar parts rotated away from each other along the C-N single bond. In this case the coordination sphere is distorted square pyramidal (T = 0.20) with the three donor sites of the L ligand and an oxo oxygen atom defining the tetragonal plane. Both the α and β crystal lattices consist of dimers which associate further to form supramolecules. The noncovalent intradimer and interdimer bonding interactions are predominantly of aromatic π-π stacking (aryl...pyridyl and pyridyl...pyridyl) and C-H...O hydrogen bonding (azomethine...oxo and aryl...phenolato) types in the α and β dimorphs, respectively. It is proposed that the low polarizability of methanol promotes π-π stacking of planar V(L) fragments, resulting in crystallization of the a form. When the polarizability is relatively high, as in acetonitrile, the β form crystallizes. The geometrically isomeric coordination spheres of the α and β forms are sustained by the respective supramolecular architectures. The Schiff base HL′ of 2-hydroxynapthaldehyde and 2-picolylamine has also afforded two forms of VO2(L′) in the same manner as for VO2(L). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Coordinating and non-coordinating anion controlled synthesis of different nuclearity cadmium(II) complexes of 2-((E)-((pyridin-2-yl)methylimino)methyl)phenol: Crystal structure and photophysical study

The tridentate Schiff base ligand 2-((E)-((pyridin-2-yl)methylimino)methyl)phenol (HL) was used to synthesize four new cadmium(II) complexes, namely [Cd4L6](ClO4)2 (1), [CdL(SCN)]n (2), [CdL(dca)]sub

Synthesis, structure, spectra and redox chemistry of iron(III) complexes of tridentate pyridyl and benzimidazolyl ligands

A series of high-spin octahedral 1:2 iron(III) complexes of Schiff bases derived from salicylaldehyde and aromatic amines and the 1:1 and 1:2 complexes of bis(pyridin-2-yl)-aza and bis(benzimidazol-2-yl)-aza and -thioether ligands have been isolated. The

From fluorogens to fluorophores by elucidation and suppression of ultrafast excited state processes of a Schiff base

Strategies have been explored for developing strongly fluorescent species out of a weakly fluorescent Schiff base, 2-(((pyridin-2-ylmethyl)imino)methyl)phenol (salampy). The locally excited enolic state of salampy undergoes an intramolecular proton transf

Directed Hydroxylation of sp2 and sp3 C-H Bonds Using Stoichiometric Amounts of Cu and H2O2

The use of copper for C-H bond functionalization, compared to other metals, is relatively unexplored. Herein, we report a synthetic protocol for the regioselective hydroxylation of sp2 and sp3 C-H bonds using a directing group, stoichiometric amounts of Cu and H2O2. A wide array of aromatic ketones and aldehydes are oxidized in the carbonyl γ-position with remarkable yields. We also expanded this methodology to hydroxylate the β-position of alkylic ketones. Spectroscopic characterization, kinetics, and density functional theory calculations point toward the involvement of a mononuclear LCuII(OOH) species, which oxidizes the aromatic sp2 C-H bonds via a concerted heterolytic O-O bond cleavage with concomitant electrophilic attack on the arene system.