137129-98-7

Usage

Uses

Used in Pharmaceutical Industry:
3-Pyridinecarboxylic acid, 6-chloro-2-methylis used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Pyridinecarboxylic acid, 6-chloro-2-methylserves as an intermediate for the production of various agrochemicals, including pesticides and herbicides. Its chemical properties make it suitable for the development of effective and targeted agricultural products.
Used in Research and Development:
3-Pyridinecarboxylic acid, 6-chloro-2-methylis also utilized in research and development for the exploration of its potential applications in various fields. Its unique structure and properties make it an interesting candidate for further studies and potential discoveries in chemistry and related disciplines.

InChI:InChI=1/C7H6ClNO2/c1-4-5(7(10)11)2-3-6(8)9-4/h2-3H,1H3,(H,10,11)

Upstream product

• 31163-12-9 ethyl 6-chloro-2-methylnicotinate 

Downstream Products

• 62366-52-3 C₇H₅Cl₂NO 
• 879088-87-6 C₁₈H₁₃Cl₂N₃O 
• 1258238-76-4 C₂₀H₁₉ClN₄O₂ 
• 879088-06-9 C₂₂H₂₃ClN₄O 
• 1258238-77-5 C₂₄H₂₆ClN₅O 
• 879088-02-5 C₂₄H₂₄ClN₅O₂ 
• 879087-95-3 C₂₁H₁₇ClN₆O 
• 851759-19-8 methyl 6-chloro-2-methylpyridine-3-carboxylate 
• 164666-68-6 3-amino-6-chloro-2-methylpyridine 
• 1204535-72-7 4-({(3S)-4-[(6-Chloro-2-methyl-3-pyridinyl)carbonyl]-3-methyl-1-piperazinyl}sulfonyl)-3-methylbenzonitrile 
• 1204535-71-6 (2S)-1-[(6-chloro-2-methyl-3-pyridinyl)carbonyl]-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1024037-43-1 6-chloro-N-cyclohexyl-2-methylnicotinamide 

Relevant academic research and scientific papers

Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): Structure-activity relationships leading to the identification of 6-((5 S,9 R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7- triazaspiro[4.4]nonan-7-yl)nico

Leukocyte function-associated antigen-1 (LFA-1), also known as CD11a/CD18 or αLβ2, belongs to the β2 integrin subfamily and is constitutively expressed on all leukocytes. The major ligands of LFA-1 include three intercellu

Second generation 2-pyridyl biphenyl amide inhibitors of the hedgehog pathway

Potent and efficacious inhibitors of the hedgehog pathway for the treatment of cancer have been prepared using the 2-pyridyl biphenyl amide scaffold common to the clinical lead GDC-0449. Analogs with polar groups in the para-position of the aryl amide ring optimized potency, had minimal CYP inhibition, and possessed good exposure in rats. Compounds 9d and 14f potently inhibited hedgehog signaling as measured by Gli1 mRNA and were found to be equivalent or more potent than GDC-0449, respectively, when studied in a Ptch+/- medulloblastoma allograft model, that is, highly dependent on hedgehog signaling.