164666-68-6Relevant articles and documents
HERBICIDES
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Page/Page column 43, (2017/10/30)
The present invention relates to herbicidally active pyridino-/pyrimidino-pyridine derivatives. The invention further provides processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, in crops of useful plants.
THIADIAZOLE MODULATORS OF S1P AND METHODS OF MAKING AND USING
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Paragraph 0235, (2017/01/26)
The invention is directed to compounds of the formula: wherein each of the variables are defined herein, as well as methods of making and using the compounds as agonists of S1P1 and/or S1P5 for instance treating an autoimmune disease.
6-chloro-3-fluoro-2-pyridine carboxylic acid synthesis
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Paragraph 0026-0027, (2017/03/14)
The invention discloses a 6-chlorine-3-fluorine-2-picolinic acid synthesis process. The main starting material is 6-chlorine-3-fluorine-2-methylpyridine.The 6-chlorine-3-fluorine-2-methylpyridine serves as the starting material, dilute sulphuric acid is a solvent, potassium dichromate is an oxidizing agent, sodium tungstate (Na2WO4 2H2O) and crown ether are a composite catalyst, after reaction is completed, a crude product is obtained through conventional post-processing, the crude product is heated to be dissolved in an alkaline aqueous solution, unreacted micro raw materials and other impurities are extracted through an organic solvent, a water layer is acidized through mineral acid, pure 6-chlorine-3-fluorine-2-picolinic acid is obtained after cooling and crystallization are carried out, the yield is high, and the quality of the product is good.