137172-64-6 Usage
Uses
Used in Pharmaceutical Development:
(3R,4S)-N-benzyl-3-hydroxy-4-methylpyrrolidine is used as a building block in the pharmaceutical industry for the development of new drugs. Its chiral nature and diverse functional groups allow for the creation of enantiomerically pure compounds, which are essential for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Organic Synthesis:
In the field of organic synthesis, (3R,4S)-N-benzyl-3-hydroxy-4-methylpyrrolidine serves as a versatile intermediate. Its unique structure and functional groups enable it to be a key component in the synthesis of complex organic molecules, contributing to the advancement of chemical research and the development of novel compounds with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 137172-64-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,1,7 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 137172-64:
(8*1)+(7*3)+(6*7)+(5*1)+(4*7)+(3*2)+(2*6)+(1*4)=126
126 % 10 = 6
So 137172-64-6 is a valid CAS Registry Number.
137172-64-6Relevant academic research and scientific papers
Fluoronaphthyridines and -quinolines as Antibacterial Agents. 5. Synthesis and Antimicrobial Activity of Chiral 1-tert-Butyl-6-fluoro-7-substituted-naphthyridones
Cesare, P. Di,Bouzard, D.,Essiz, M.,Jacquet, J. P.,Ledoussal, B.,et al.
, p. 4205 - 4213 (2007/10/02)
A series of novel 7-substituted-1-tert-butyl-6-fluoronaphthyridone-3-carboxylic acids has been prepared.These derivatives are characterized by chiral aminopyrrolidine substituents at the 7 position.In this paper we report the full details of the asymmetric synthesis of this series of compounds.Structure-activity relationship studies indicate that the absolute stereochemistry at the asymmetric centers of the pyrrolidine ring is critical for maintaining good activity.Compounds 60 and 61 (3-amino-4-methylpyrrolidine enantiomers) were selected for preclinical evaluation.
Isoindoline derivatives
-
, (2008/06/13)
Optically active 8-methoxyquinolonecarboxylic acids represented by the formula (I) wherein R1 is lower alkyl have been found to possess potent antibacterial activity against both Gram-negative and Gram-positive bacteria. The compounds may be synthesized from novel optically active intermediates.
