137172-65-7 Usage
Uses
Used in Pharmaceutical Research:
(3S,4R)-4-methyl-1-(phenylmethyl)-3-Pyrrolidinol is utilized as an intermediate in the synthesis of various pharmaceutical compounds due to its unique chiral properties. Its ability to influence the stereochemistry of target molecules makes it valuable in the development of enantiomerically pure drugs, which can have significant implications for improving drug efficacy and reducing side effects.
Used in Chemical Research:
In the field of chemical research, (3S,4R)-4-methyl-1-(phenylmethyl)-3-Pyrrolidinol serves as a versatile building block for the creation of novel chiral molecules. Its distinctive structure allows researchers to explore its potential in asymmetric synthesis, catalysis, and the development of new chiral ligands or catalysts, further expanding the scope of enantioselective chemical reactions.
Used in Chiral Analysis:
(3S,4R)-4-methyl-1-(phenylmethyl)-3-Pyrrolidinol is employed as a reference compound in chiral analysis and chromatographic techniques. Its well-defined stereochemistry makes it an ideal standard for calibrating instruments and developing methods for the separation and analysis of enantiomers in complex mixtures, which is crucial in quality control and the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 137172-65-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,1,7 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 137172-65:
(8*1)+(7*3)+(6*7)+(5*1)+(4*7)+(3*2)+(2*6)+(1*5)=127
127 % 10 = 7
So 137172-65-7 is a valid CAS Registry Number.
137172-65-7Relevant academic research and scientific papers
Fluoronaphthyridines and -quinolines as Antibacterial Agents. 5. Synthesis and Antimicrobial Activity of Chiral 1-tert-Butyl-6-fluoro-7-substituted-naphthyridones
Cesare, P. Di,Bouzard, D.,Essiz, M.,Jacquet, J. P.,Ledoussal, B.,et al.
, p. 4205 - 4213 (2007/10/02)
A series of novel 7-substituted-1-tert-butyl-6-fluoronaphthyridone-3-carboxylic acids has been prepared.These derivatives are characterized by chiral aminopyrrolidine substituents at the 7 position.In this paper we report the full details of the asymmetric synthesis of this series of compounds.Structure-activity relationship studies indicate that the absolute stereochemistry at the asymmetric centers of the pyrrolidine ring is critical for maintaining good activity.Compounds 60 and 61 (3-amino-4-methylpyrrolidine enantiomers) were selected for preclinical evaluation.
Isoindoline derivatives
-
, (2008/06/13)
Optically active 8-methoxyquinolonecarboxylic acids represented by the formula (I) wherein R1 is lower alkyl have been found to possess potent antibacterial activity against both Gram-negative and Gram-positive bacteria. The compounds may be synthesized from novel optically active intermediates.
