13719-61-4

Basic information

• Product Name: 2-Chloro-5-methoxybenzaldehyde
• Synonyms: 2-Chloro-5-methoxybenzaldehyde;2-Chloro-5-Methoxybenzaldehyde(WX622079)
• CAS NO: 13719-61-4
• Molecular Formula: C₈H₇ClO₂
• Molecular Weight: 171
• Mol File: 13719-61-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 62℃
• Boiling Point: 262℃
• Flash Point: 117℃
• Appearance: /
• Density: 1.244
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Chloro-5-methoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-methoxybenzaldehyde(13719-61-4)
• EPA Substance Registry System: 2-Chloro-5-methoxybenzaldehyde(13719-61-4)

Safety Data

• Hazardous Substances Data: 13719-61-4(Hazardous Substances Data)

Usage

General Description

2-Chloro-5-methoxybenzaldehyde, also known as o-Chloro-p-anisaldehyde, is an organic compound with the chemical formula C8H7ClO2. It is a pale yellow liquid that is commonly used in the synthesis of pharmaceuticals and other organic compounds. This chemical is widely used as an intermediate in the production of various fragrances and flavors, as well as in the manufacturing of dyes and agrochemicals. It is also used as a reagent in organic chemistry reactions, particularly in the preparation of heterocyclic compounds. 2-Chloro-5-methoxybenzaldehyde is known to have a strong odor and should be handled with caution due to its potential toxicity and irritant properties.

Upstream product

• 75-17-2 formaldoxime 
• 2401-24-3 2-chloro-5-methoxyaniline 
• 77-78-1 dimethyl sulfate 
• 623-12-1 4-chloromethoxybenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 101252-66-8 (2-chloro-5-methoxyphenyl)methanol 
• 54810-63-8 methyl (2-chloro-5-methoxy)benzoate 
• 591-31-1 3-methoxy-benzaldehyde 
• 96-96-8 4-methoxy-2-nitroaniline 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 59-50-7 4-Chloro-3-methylphenol 
• 13334-71-9 1-chloro-4-methoxy-2-methylbenzene 
• 3771-13-9 2-(bromomethyl)-1-chloro-4-methoxybenzene 
• 507-40-4 tert-butylhypochlorite 

Downstream Products

• 6280-89-3 2-chloro-5-methoxybenzoic acid 
• 127667-00-9 2-chloro-5-methoxybenzonitrile 
• 882674-30-8 2-(2-chloro-5-methoxyphenyl)ethan-1-amine 
• 93899-68-4 1-(2-Chlor-5-methoxy-phenyl)-2-(4-chlor-phenyl)-ethanol 
• 89691-65-6 1-(2-Chloro-5-methoxy-phenyl)-ethanol 
• 89106-49-0 1-(2-Chloro-5-methoxy-phenyl)-propan-1-ol 
• 105728-93-6 5,10,15,20-tetrakis(2-chloro-5-methoxyphenyl)porphyrin 

Relevant articles and documents

In vitro photodynamic activity of 5,15-bis(3-Hydroxyphenyl)porphyrin and its halogenated derivatives against cancer cells

5,15-Diarylporphyrins (1-5) with hydroxyl groups and halogens as substituents were prepared by condensation between unsubstituted dipyrromethane and halogenated m-hydroxybenzaldehydes. Photophysical properties show that the nonhalogenated porphyrin 1 has higher fluorescence yield but lower singlet oxygen formation quantum yield than the halogenated derivatives due to the heavy atom effect. The in vitro activity of these derivatives was tested against WiDr colorectal adenocarcinoma and A375 melanoma cancer cells. All porphyrins present a much higher phototoxicity than Photofrin with IC 50 values lower than the 50 nm level for WiDr cells and 25 nm level for A375 cancer cells. The most photoactive compound is the nonhalogenated porphyrin 1 which also presents the highest uptake. Halogenated derivatives present much lower uptakes than 1. However, their photoactivity is similar to compound 1 showing that their intrinsic photoactivity (ISP) is very high. Iodinated compound 4 presents the highest ISP. The greater ability of these porphyrins to destroy cancer cells could be related to their photophysical and photochemical properties.

SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS

Compounds of the general formula:processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

A method for the preparation of oxadiazole compounds (by machine translation)

The invention discloses a oxadiazole compound N - ((3 - (2 - chloro - 5 - methoxyphenyl) - 1, 2, 4 - oxadiazol - 5 - yl) methyl) aminoethane preparation method, in order to 4 - chlorophenyl methyl ether as the starting material, through the aldehyde group, oximation, eliminate, addition, ring, substituted reaction to obtain the target product 7, the product of the invention as the template molecule to synthesize a variety of compound library. (by machine translation)