13719-80-7Relevant academic research and scientific papers
Diversity oriented approach to polycyclic compounds through the diels-alder reaction and the Suzuki coupling
Kotha, Sambasivarao,Misra, Shilpi,Srinivas, Venu
scheme or table, p. 4052 - 4062 (2012/09/07)
A diversity oriented strategy has been demonstrated to deliver small "drug like" molecules using alkylation, Diels-Alder reaction, and Suzuki-Miyaura cross-coupling as key steps. This methodology allows access a wide range of molecules using simple scaffolds such as indanes, tetralins and tetrahydroisoquinolines, which can enhance the chemical space for potential therapeutic molecules.
Trifluoro-3-hydroxy-1H-indazolecarboxylic acids and esters from perfluorinated benzenedicarboxylic acids
Medina, Carlos Perez,Lopez, Concepcion,Claramunt, Rosa M.,Elguero, Jose
scheme or table, p. 890 - 899 (2010/04/23)
Twelve new 3-hydroxyindazoles, each bearing three fluorine substituents and a CO2R group (R = H, CH3, C2H5) distributed around its 4-, 5-, 6-, and 7-positions, have been synthesized. They were studied by NMR in
