13719-82-9Relevant academic research and scientific papers
Synthesis and characterization of electron-deficient pentacenes
Swartz, Christopher R.,Parkin, Sean R.,Bullock, Joseph E.,Anthony, John E.,Mayer, Alex C.,Malliaras, George G.
, p. 3163 - 3166 (2005)
(Chemical Equation Presented) Halogen functional groups on pentacene can be used both as synthetic handles for further functionalization as well as to tune the π-stacking in these systems. The halogenated pentacene derivatives described here (X = Br, X′ =
IDO/TDO Inhibitor
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Paragraph 0334; 0337; 0338; 0363; 0364, (2020/08/19)
A compound of formula (I) given below or a pharmaceutically acceptable salt of the compound is useful as an IDO/TDO inhibitor. Thus, the compound of formula (I) or the pharmaceutically acceptable salt of the compound can be used as, for example, a therapeutic agent for a disease or a disorder selected from tumor, infectious disease, neurodegenerative disorder, cataract, organ transplant rejection, autoimmune disease, postoperative cognitive impairment, and disease related to women's reproductive health [in the following formula (I), ring A represents an aromatic ring, an aliphatic ring, a heterocyclic ring, or a condensed ring of two or more rings selected from an aromatic ring, an aliphatic ring and a heterocyclic ring; X, R1 and R2 represent a substituent on a ring atom constituting ring A; m represents an integer of 0 to 6; X represents, for example, a halogen atom; and R1 and R2 are the same or different and are selected from, for example, the group consisting of groups of formula (a) or formula (b); and in the following formula (a) and formula (b), Y is selected from the group consisting of O, S, and Se, Z is selected from the group consisting of O, S, and Se, n represents an integer of 1 to 8, r represents an integer of 1 to 8, s represents an integer of 1 to 8, R4 represents, for example, —C(═NH)—HN2, and R6 represents, for example, a substituted or unsubstituted aryl group].
Diversity oriented approach to polycyclic compounds through the diels-alder reaction and the Suzuki coupling
Kotha, Sambasivarao,Misra, Shilpi,Srinivas, Venu
, p. 4052 - 4062 (2012/09/07)
A diversity oriented strategy has been demonstrated to deliver small "drug like" molecules using alkylation, Diels-Alder reaction, and Suzuki-Miyaura cross-coupling as key steps. This methodology allows access a wide range of molecules using simple scaffolds such as indanes, tetralins and tetrahydroisoquinolines, which can enhance the chemical space for potential therapeutic molecules.
Phenoxybenzyl 2-[2-(2-hydroxy)indanyl]-3-methyl-butanoates
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, (2008/06/13)
Esters of α-indenyl substituted aliphatic acids, intermediates therefor, synthesis thereof, and the use of said esters and compositions thereof for the control of pests.
Isoindolinyl derivatives
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, (2008/06/13)
Esters of lower alkanoic acids substituted at the α-position with isoindoline or tetrahydroisoquinoline, and intermediates therefor, useful as pesticides.
