1372129-45-7

Basic information

• Product Name: C₁₇H₁₅NO₄
• CAS NO: 1372129-45-7
• Molecular Weight: 297.31
• Mol File: 1372129-45-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₅NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₅NO₄(1372129-45-7)
• EPA Substance Registry System: C₁₇H₁₅NO₄(1372129-45-7)

Safety Data

• Hazardous Substances Data: 1372129-45-7(Hazardous Substances Data)

Upstream product

• 31593-52-9 2-benzyl-1,3-dithiane 
• 119340-78-2 2-benzyl-2-trimethylsilyl-1,3-dithiane 
• 100-39-0 benzyl bromide 
• 56583-94-9 (phenylacetyl)trimethylsilane 
• 636-98-6 p-nitrobenzene iodide 
• 665004-92-2 (Z)-2-methyl-3-trimethylsilyl-4-phenyl-2-butenoic acid 

Relevant articles and documents

Palladium-catalyzed fluoride-free cross-coupling of intramolecularly activated alkenylsilanes and alkenylgermanes: Synthesis of tamoxifen as a synthetic application

We have demonstrated that intramolecular hypercoordination of a carboxylic acid is a powerful activation strategy for the palladium-catalyzed cross-coupling reaction of trialkyl(vinyl)silanes and trialkyl(vinyl)germanes under fluoride-free conditions. Z-β-Trialkylsilyl- and Z-β- trialkylgermylacrylic acids, synthesized stereoselectively by olefination with ynolates, are highly stable and useful reagents for cross-coupling with a variety of aryl iodides to provide tetrasubstituted olefins possessing different carbon substituents in a stereocontrolled and diversity-oriented manner. An application to a stereoselective synthesis of (Z)-tamoxifen is also reported. Copyright