137219-86-4 Usage
Description
(R)-DM-BINAP, also known as (R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl, is a chiral phosphine-based ligand derived from binaphthyl. It is characterized by its unique structure, which consists of two naphthyl groups connected by a phosphine bridge. This structure endows (R)-DM-BINAP with high enantioselectivity and stability, making it a valuable compound in various chemical reactions and applications.
Uses
Used in Pharmaceutical Industry:
(R)-DM-BINAP is used as a chiral ligand for the synthesis of various pharmaceutical compounds. Its high enantioselectivity allows for the production of enantiomerically pure compounds, which is crucial in the development of effective and safe drugs. The ligand plays a vital role in asymmetric catalysis, enabling the selective formation of desired enantiomers in chemical reactions.
Used in Chemical Industry:
(R)-DM-BINAP is used as a catalyst in the preparation of various chemical compounds, such as chiral intermediates and specialty chemicals. Its high stability and enantioselectivity make it an ideal choice for industrial applications where the production of high-quality, enantiomerically pure products is required.
Used in Research and Development:
(R)-DM-BINAP is used as a research tool in the development of new asymmetric catalytic reactions and the study of reaction mechanisms. Its unique structure and properties allow chemists to explore new reaction pathways and improve the efficiency of existing processes.
Check Digit Verification of cas no
The CAS Registry Mumber 137219-86-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,2,1 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 137219-86:
(8*1)+(7*3)+(6*7)+(5*2)+(4*1)+(3*9)+(2*8)+(1*6)=134
134 % 10 = 4
So 137219-86-4 is a valid CAS Registry Number.
137219-86-4Relevant articles and documents
Synthesis and application of N-3,5-dinitrobenzoyl and C3 symmetric diastereomeric chiral stationary phases
Ryoo, Jae Jeong,Yu, Jeong Jae
, (2022/01/20)
Three diastereomeric chiral compounds, namely, (R,R)-(+)-2-amino-1,2-diphenylethanol, (1S,2R)-(+)-2-amino-1,2-diphenylethanol, and (1R,2R)-(+)-1,2-diphenylethylenediamine were used as starting materials for preparing three N-3,5-dinitrobenzoyl derivative
A 2,2 the [...] -bis [(3,5- xylyl ) phosphorus] dinaphthalene method for the preparation of
-
Paragraph 0028; 0042; 0043, (2017/02/28)
The invention relates to the field of organic synthesis, and in particular relates to a method for preparing 2, 2'-bis [(3, 5-xylyl) phosphorus) dinaphthalene. The method comprises the following steps: preparing N-methyl piperazine phosphorus dichloride h
Improved syntheses of phosphine ligands by direct coupling of diarylbromophosphine with organometallic reagents
Liu, Lei,Wu, Hai-Chen,Yu, Jin-Quan
scheme or table, p. 10828 - 10831 (2011/11/04)
Br versus Cl: It is found that the use of diarylbromophosphines instead of diarylchlorophosphines is crucial for their direct coupling with binaphthylmagnesium bromide or BINOL triflate. This finding has led to an improved preparation of both electron-deficient BINAP-type phosphine ligands and several important Buchwald's ligands. Copyright
